198630-95-4

Upstream product

• 56-23-5 tetrachloromethane 
• 2146-61-4 3-methoxyphenethyl bromide 
• 5020-41-7 2-(3-methoxyphenyl)-ethanol 
• 7789-69-7 phosphorus pentabromide 
• 117565-90-9 methyl 2-(2'-bromo-5'-methoxyphenyl)acetate 
• 86826-93-9 2-(2-bromo-5-methoxyphenyl)acetic acid 
• 27387-23-1 5-methoxy-2-bromophenylacetonitrile 
• 19614-12-1 2-bromo-5-methoxybenzyl bromide 
• 27060-75-9 4-bromo-3-methylanisole 
• 75534-35-9 2-(2-bromo-5-methoxyphenyl)ethan-1-ol 

Downstream Products

• 198630-97-6 Ethyl 3-[2-(2-bromo-5-methoxyphenyl)ethyl]-2-methyl-4-oxocyclohex-2-enecarboxylate 
• 192635-65-7 2-<2-(2-Bromo-5-methoxyphenyl)ethyl>-3,3-dimethylcyclohexanone 
• 198631-06-0 Methyl 2-<2-(2-bromo-5-methoxyphenyl)ethyl>-1-methyl-3-oxocyclohexanecarboxylate 
• 198631-00-4 2-[2-(2-Bromo-5-methoxyphenyl)ethyl]-3-methylcyclohex-2-enone 
• 198631-10-6 2-[2-(2-Bromo-5-methoxyphenyl)ethyl]-3,3-dimethyl-1-methylenecyclohexane 
• 928310-07-0 C₂₆H₂₃BrN₄O₂ 
• 928309-83-5 C₂₅H₂₁BrN₄O₂ 

Relevant academic research and scientific papers

Highly diastereoselective synthesis of tetralin-fused spirooxindoles via lewis acid-catalyzed C(sp3)H bond functionalization

A highly diastereoselective synthesis of tetralin-fused spirooxindole derivatives was described. Treatment of benzylidene oxindoles with a catalytic amount of Sc(OTf)3 in refluxing hexane afforded the target compounds in good chemical yields with excellent diastereoselectivities (up to >20:1). Detailed investigation of the reaction mechanism revealed that both interconversion of the two diastereomers and their solubility difference in reaction medium were the key to achieving excellent diastereoselectivities.

Regioselective aryl radical cyclisation. Part 2. Synthesis of octahydro-1H-dibenzo[a,d]cycloheptenes through 7-endo ring closure

A simple convergent synthesis of trans- and cis-octahydro-1H-dibenzo[a,d]cycloheptenes 15a-c and 16a-c and 20a-c and 21a-c through implementation of a regioselective 7-endo-trig-aryl radical cyclisation of the respective 2-(o-bromoarylethyl)-1-methylenecy