198649-62-6 Usage
Explanation
The molecular formula represents the number of atoms of each element present in a molecule. In this case, the compound has 15 carbon (C), 21 hydrogen (H), 1 nitrogen (N), and 2 oxygen (O) atoms.
2. Spiro compound
Explanation
A spiro compound is characterized by the presence of two non-adjacent stereocenters and a cyclic structure. This means that the two stereocenters are connected in a way that they do not share a common bond.
3. Presence of a phenyl group
Explanation
The phenyl group is a benzene ring with one hydrogen atom replaced by a carbon-carbon single bond. This suggests that the compound has a benzene ring in its structure, which is a common structural feature in many organic compounds.
4. Heterocyclic compound
Explanation
A heterocyclic compound is a cyclic compound that contains atoms of at least two different elements as part of its ring structure. In this case, the compound contains carbon, hydrogen, nitrogen, and oxygen atoms in its ring structure.
5. Building block in organic chemistry
Explanation
1,4-Dioxa-8-azaspiro[4.5]decane, 8-phenylis used as a building block in organic chemistry for the synthesis of various complex organic molecules. This means that it can be used as a starting material or intermediate in the formation of more complex structures.
6. Potential applications in the pharmaceutical industry
Explanation
Due to its unique structure and properties, 1,4-Dioxa-8-azaspiro[4.5]decane, 8-phenylmay have potential applications in the pharmaceutical industry as a precursor for the development of new drug compounds. This means that it could be used as a starting point for designing and synthesizing new drugs with specific therapeutic properties.
Check Digit Verification of cas no
The CAS Registry Mumber 198649-62-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,9,8,6,4 and 9 respectively; the second part has 2 digits, 6 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 198649-62:
(8*1)+(7*9)+(6*8)+(5*6)+(4*4)+(3*9)+(2*6)+(1*2)=206
206 % 10 = 6
So 198649-62-6 is a valid CAS Registry Number.
198649-62-6Relevant articles and documents
Palladium-catalyzed c(sp2)-n bond cross-coupling with triaryl phosphates
Chen, Zicong,Chen, Xiangmeng,So, Chau Ming
, (2019/05/22)
The first general palladium-catalyzed amination of aryl phosphates is described. The combination of MorDalPhos with [Pd(-cinnamyl)Cl]2 enables the amination of electron-rich, electron-neutral, and electron-poor aryl phosphates with a board range of aromatic, aliphatic, and heterocyclic amines. Common functional groups such as ether, keto, ester, and nitrile show an excellent compatibility in this reaction condition. The solvent-free amination reactions are also successful in both solid coupling partners. The gram-scale cross-coupling is achieved by this catalytic system.
Robust Buchwald-Hartwig amination enabled by ball-milling
Cao, Qun,Nicholson, William I.,Jones, Andrew C.,Browne, Duncan L.
supporting information, p. 1722 - 1726 (2019/02/20)
An operationally simple mechanochemical method for the Pd catalysed Buchwald-Hartwig amination of arylhalides with secondary amines has been developed using a Pd PEPPSI catalyst system. The system is demonstrated on 30 substrates and applied in the context of a target synthesis. Furthermore, the performance of the reaction under aerobic conditions has been probed under traditional solution and mechanochemical conditions, the observations are discussed herein.
NOVEL 5 or 8-SUBSTITUTED IMIDAZO [1, 5-a] PYRIDINES AS SELECTIVE INHIBITORS OF INDOLEAMINE AND/OR TRYPTOPHANE 2, 3-DIOXYGENASES
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Paragraph 0390; 0391, (2018/04/20)
Disclosed herein are 5 or 8-substituted imidazo [1, 5-a] pyridines and pharmaceutical compositions comprising at least one such 5 or 8-substituted imidazo [1, 5-a] pyridines, processes for the preparation thereof, and the use thereof in therapy. Disclosed herein are certain 5 or 8-substituted imidazo [1, 5-a] pyridines that can be useful for inhibiting indoleamine 2, 3-dioxygenase and/or tryptophane 2, 3-dioxygenase and for treating diseases or disorders mediated thereby.
