1987-40-2

Basic information

• Product Name: (2S,3R,4R)-2-(N-benzoyl)amino-octadecane-1,3,4-triol
• Synonyms: (2S,3R,4R)-2-(N-benzoyl)amino-octadecane-1,3,4-triol
• CAS NO: 1987-40-2
• Molecular Weight: 421.621
• Mol File: 1987-40-2.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: (2S,3R,4R)-2-(N-benzoyl)amino-octadecane-1,3,4-triol(CAS DataBase Reference)
• NIST Chemistry Reference: (2S,3R,4R)-2-(N-benzoyl)amino-octadecane-1,3,4-triol(1987-40-2)
• EPA Substance Registry System: (2S,3R,4R)-2-(N-benzoyl)amino-octadecane-1,3,4-triol(1987-40-2)

Safety Data

• Hazardous Substances Data: 1987-40-2(Hazardous Substances Data)

Upstream product

• 554-62-1 D-ribo-phytosphingosine 
• 98-88-4 benzoyl chloride 
• 13276-30-7 D-ribo-2-Benzamido-1.3.4-trihydroxyoctadec-8-in 
• 13276-29-4 N-((3R,4S,5R)-2,4-Dihydroxy-5-tetradecyl-tetrahydro-furan-3-yl)-benzamide 
• 13276-35-2 N-((3R,4S,5R)-2,4-Dihydroxy-5-tetradec-4-ynyl-tetrahydro-furan-3-yl)-benzamide 
• 13276-34-1 N-((2R,3R,4S,5R)-4-Hydroxy-2-methoxy-5-tetradec-4-ynyl-tetrahydro-furan-3-yl)-benzamide 
• 13266-04-1 N-((2R,3R,4S,5R)-4-Hydroxy-2-methoxy-5-tetradecyl-tetrahydro-furan-3-yl)-benzamide 

Downstream Products

• 572922-32-8 (2S,3R,4R)-2-(N-benzoyl)amino-3,4-di-O-benzoyl-1-O-trityl-octadecane-1,3,4-triol 
• 572922-33-9 (2S,3R,4R)-2-(N-benzoyl)amino-3,4-di-O-benzoyl-octadecane-1,3,4-triol 
• 572922-34-0 2-phenyl-4-(S)-[(1R,2R)-1,2-di(benzoyloxy)hexadecyl]-1,3-oxazoline 
• 572922-36-2 1-[4-(S)-(2-Phenyl-4,5-dihydro-oxazol-4-yl)]-(1 S,2R)-1-hydroxy-2-O-mesyl-hexadecane 
• 572922-35-1 2-phenyl-4-(S)-[(1R,2R)-1,2-dihydroxyhexadecyl]-1,3-oxazoline 
• 572922-31-7 (2S,3R,4R)-2-(N-benzoyl)amino-1-O-trityl-octadecane-1,3,4-triol 

Relevant articles and documents

Effective, high-yielding, and stereospecific total synthesis of D-erythro-(2R,3S)-sphingosine from D-ribo-(2S,3S,4R)-phytosphingosine

The synthesis of naturally occurring D-erythro-(2R,3S,4E)-sphingosine from commercially available D-ribo-(2S,3S,4R)-phytosphingosine is described. The key step in the reaction sequence comprises TMSI/DBN promoted regio- and stereoselective oxirane opening of intermediate 2-phenyl-4-(S)-[(1S,2S)-1,2- epoxyhexadecyl]-1,3-oxazoline followed by the in situ trans-elimination of 2-phenyl-4-(S)-[(1S,2R)-1,2-dideoxy-2-iodo-1-trimethylsilyloxyhexadecyl]-1, 3-oxazoline.

Process for the synthesis of sphingosine

This invention relates to a method for the production of a sphingoid base according to formula comprising the steps of (1) dissolving a starting compound according to formula III or a salt thereof in a substantially inert solvent, (2) protecting the NHsu