572922-35-1

Basic information

• Product Name: 1,2-Hexadecanediol, 1-[(4S)-4,5-dihydro-2-phenyl-4-oxazolyl]-, (1S,2R)-
• CAS NO: 572922-35-1
• Molecular Formula: C25H41NO3
• Molecular Weight: 403.605
• Mol File: 572922-35-1.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 1,2-Hexadecanediol, 1-[(4S)-4,5-dihydro-2-phenyl-4-oxazolyl]-, (1S,2R)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1,2-Hexadecanediol, 1-[(4S)-4,5-dihydro-2-phenyl-4-oxazolyl]-, (1S,2R)-(572922-35-1)
• EPA Substance Registry System: 1,2-Hexadecanediol, 1-[(4S)-4,5-dihydro-2-phenyl-4-oxazolyl]-, (1S,2R)-(572922-35-1)

Safety Data

• Hazardous Substances Data: 572922-35-1(Hazardous Substances Data)

Upstream product

• 98-88-4 benzoyl chloride 
• 554-62-1 D-ribo-phytosphingosine 
• 5333-86-8 ethyl benzimidate hydrochloride 
• 572922-34-0 2-phenyl-4-(S)-[(1R,2R)-1,2-di(benzoyloxy)hexadecyl]-1,3-oxazoline 
• 572922-32-8 (2S,3R,4R)-2-(N-benzoyl)amino-3,4-di-O-benzoyl-1-O-trityl-octadecane-1,3,4-triol 
• 572922-31-7 (2S,3R,4R)-2-(N-benzoyl)amino-1-O-trityl-octadecane-1,3,4-triol 
• 572922-33-9 (2S,3R,4R)-2-(N-benzoyl)amino-3,4-di-O-benzoyl-octadecane-1,3,4-triol 
• 1987-40-2 (2S,3R,4R)-2-(N-benzoyl)amino-octadecane-1,3,4-triol 

Downstream Products

• 756479-86-4 2-phenyl-4-(S)-[(1R,2R)-1-hydroxy-2-tosyloxy-hexadecyl]-1,3-oxazoline 
• 572922-36-2 1-[4-(S)-(2-Phenyl-4,5-dihydro-oxazol-4-yl)]-(1 S,2R)-1-hydroxy-2-O-mesyl-hexadecane 
• 123-78-4 (2S,3R,4E)-2-amino-4-octadecene-1,3-diol 
• 78739-31-8 threo-4-(1-hydroxy-2-hexadecenyl)-2-phenyl-Δ²-oxazoline 

Relevant articles and documents

A rapid and efficient synthesis of D-erythro-sphingosine from D-ribo-phytosphingosine

In this paper we describe the concise synthesis of D-erythro-sphingosine starting from the readily available chiral building block D-ribo- phytosphingosine. The title compound is the ubiquitous sphingolipid from which most mammalian ceramides are derived. Our work is based on the existing literature in which the same sphingoid base is used as a starting point and culminates in what we believe is the most efficient synthesis of D-erythro-sphingosine reported to date.

A process for the synthesis of sphingosine

This invention relates to a method for the production of a sphingoid base according to formula comprising the steps of(1) dissolving a starting compound according to formula III or a salt thereof in a substantially inert solvent,(2) protecting the NH2 group with a NH2 protecting group,(3) activating C4 HR3' for an elimination reaction with C5HR4,(4) causing an elimination reaction to take place to form a double bond between the C4 and C5 carbon atom,(5) removing the NH2 protecting group.