19870-71-4

Basic information

• Product Name: ilexgenin B
• CAS NO: 19870-71-4
• Molecular Weight: 472.709
• Mol File: 19870-71-4.mol

Chemical Properties

• CAS DataBase Reference: ilexgenin B(CAS DataBase Reference)
• NIST Chemistry Reference: ilexgenin B(19870-71-4)
• EPA Substance Registry System: ilexgenin B(19870-71-4)

Safety Data

• Hazardous Substances Data: 19870-71-4(Hazardous Substances Data)

Upstream product

• 83725-19-3 ilexsaponin B₁ 
• 108906-69-0 ilexsaponin B₂ 
• 13850-16-3 euscaphic acid 
• 53155-25-2 tormentic acid 
• 121467-43-4 3β,19α,23-trihydroxyurs-12-en-28-oic acid 
• 83725-24-0 3β,19α-dihydroxyurs-12-en-28-oic acid 28-β-D-glucopyranosyl ester 
• 145022-84-0 Ilexoside VIII 
• 145022-82-8 Ilexoside VI 
• 145022-83-9 Ilexoside VII 

Downstream Products

• 14511-72-9 (1R,2S,4aS,6aS,6bR,10S,12aR,14bS)-1,10-Dihydroxy-1,2,6a,6b,9,9,12a-heptamethyl-1,3,4,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,13,14b-octadecahydro-2H-picene-4a-carboxylic acid methyl ester 
• 14511-72-9 pomolic acid 3β-acetate 
• 13849-90-6 pomonic acid 
• 6812-98-2 3β-hydroxyurs-12,19(20)-dien-28-oic acid 

Relevant articles and documents

New Biologically Active Triterpenoid Saponins from Scabiosa tschiliensis

Eleven new triterpenoid saponins, scabiosaponins A-K (1-11), and hookerosides A (12) and B (13) were isolated from the whole plants of Scabiosa tschiliensis. The structures of the new compounds were established on the basis of extensive NMR (DEPT, DQF-COSY, HETCOR, TOCSY, HMQC, HMQC-TOCSY, HMBC, and NOESY) and MS studies coupled with chemical degradations. The biological activity of compounds 1-10, 12, and 13 and prosapogenin 1b were examined against pancreatic lipase. Scabiosaponins E, F, G, I (5, 6, 7, 9), hookerosides A, B (12, 13), and prosapogenin 1b all exhibited strong inhibition of pancreatic lipase in vitro.

En route to anti-glioblastoma active pomolic acid

Tormentic acid (3) can be easily photo-reduced by Saito's procedure and is an ideal starting material for the straightforward synthesis of pomolic acid (1).

A remarkably simple and convergent partial synthesis of pomolic acid

Mixtures of tormentic and euscaphic acid can be used to access pomolic acid using a convergent synthetic approach. This approach constitutes at present the best and shortest route to pomolic acid.

Triterpenoid saponins from Ilex mamillata C.Y. Wu ex C.J. Tseng

Two new triterpenoid saponins, ilemaminosides A and B (1 and 2) along with six known saponins (3-8) were isolated from 70% ethanolic extract of the leaves of Ilex mamillata C.Y. Wu ex C.J. Tseng. The new saponins were characterised as 3-O -α- L-arabinopyranosyl-ilexgenin B (1) and 3-O-β-D- glucopyranosyl-(1→3) -α-L-arabinopyranosyl-ilexgenin B (2). The structures of compounds 1 and 2 were elucidated on the basis of the chemical and spectroscopic methods, and the structures of known compounds were identified by comparison of their spectroscopic data with those reported in the literature. The compounds showed inhibitory activities in anti-inflammatory assay invitro with IC50 values in the range 25.37-38.33gmL1.

Triterpenoid saponins from Ilex latifolia

Three new triterpenoid saponins, latifolosides F, G, H were isolated from the leaves of Ilex latifolia. Their structures were elucidated on the basis of chemical and spectral evidence. Latifoloside F was determined to be 3-O-[α-L-rhamnopyranosyl(1-2)]-[β-D-glucopyranosyl(1-3)-]-α-L- arabinopyranosyl ilexgenin B 28-O-[α-L-rhamnopyranosyl(1-2)]-β-D- glucopyranoside. Latifoloside G was 3-O-[α-L-rhamnopyranosyl(1-2)]-[β-D- glucopyranosyl(1-3)-]-α-L-arabinopyranosyl pomolic acid 28-O-[α-L- rhamnopyranosyl(1-2)]-β-D-glucopyranoside. Latifolioside H(3) was 3-O-[α- L-rhamnopyranosyl(1-2)]-[β-D-glucopyranosyl(1-3)-]-α-L-arabinopyranosyl siaresinolic acid 28-O-[α-L-rhamnopyranosyl(1-2)]-β-D-glucopyranoside.

Triterpenoid saponins from the leaves of Ilex latifolia

Five new triterpenoid saponins latifolosides A-E were isolated from the leaves of Ilex latifolia, along with a known compound. Their chemical structures have been elucidated on the basis of the chemical and spectral methods.

Triterpenoid saponins of aquifoliaceous plants. VIII. Ilexosides XXIX-XXXII from the leaves of Ilex rotunda THUNB.

From the fresh leaves of Ilex rotunda, were isolated four new saponins named ilexosides XXIX-XXXII, together with the known saponins pedunculoside, ziyu-glycoside I, suavissimoside F1 and chikusetsusaponin IVa. Their structures were established on the basis of spectral and chemical evidence.

TRITERPENE SAPONINS FROM FRUIT OF ILEX CRENATA

From the fresh fruits of Ilex crenata have been isolated six new saponins named ilexosides III-VIII, respectively, along with the known saponin, ilexoside II.Their structures were established on the basis of spectral and chemical evidence. Key words: Ilex crenata; Aquifoliaceae; pentacyclic triterpene; ilexoside; pomolic acid; bisdesmoside.

TRITERPENES FROM ILEX ROTUNDA FRUITS

Two new triterpenes have been isolated from the fruits of Ilex rotunda along with three known triterpenoids ulsolic acid, rotundic acid and peduncloside.Their structures were characterized as 3β,19α,24-trihydroxyurs-12-ene-28-oic acid and 3β,19α-dihydroxyurs-12-ene-23,28-dioic acid by spectral and chemical means. - Keywords: Ilex rotunda; Aquifoliaceae; pentacyclic triterpene; rotungenic acid; ulsolic acid; rotundic acid; peduncloside.