198706-76-2

Upstream product

• 151263-85-3 7-O-benzyl-6-deoxy-3,4-O-isopropylidene-1-O-triphenylmethyl-D-xyloheptulose 
• 148324-09-8 7-benzyloxy-1,(2R):(3R,4R)-diisopropylidenedioxy-(5R)-p-methoxyphenylmethoxyheptane 
• 85325-93-5 (4R,4'R,5R)-2,2,2',2'-tetramethyl-5-[(R)-oxiran-2-yl]-4,4'-bis(1,3-dioxolane) 
• 148324-10-1 7-benzyloxy-(2R)-hydroxy-(3R,4R)-isopropylidenedioxy-(5R)-p-methoxyphenylmethoxy-1-triphenylmethoxyheptane 
• 148324-08-7 1,(2R):(3R,4R)-diisopropylidenedioxy-(5R)-p-methoxyphenylmethoxy-7,7-propylenedithioheptane 
• 148324-17-8 7-benzyloxy-1,(2R)-dihydroxy-(3R,4R)-isopropylidenedioxy-(5R)-p-methoxyphenylmethoxyheptane 
• 85325-92-4 1,2:3,4-di-O-isopropylidene-6-O-p-toluenesulfonyl-D-mannitol 
• 148324-16-7 1,(2R):(3R,4R)-diisopropylidenedioxy-7-hydroxy-(5R)-p-methoxyphenylmethoxyheptane 
• 148324-15-6 1,(2R):(3R,4R)-diisopropylidenedioxy-6-formyl-(5R)-p-methoxyphenylmethoxyheptane 
• 148324-13-4 6-O-benzyl-5-deoxy-1,2-O-isopropylidene-3-O-methanesulfonyl-D-glucofuranose 
• 148324-14-5 2-Deoxy-4,5:6,7-di-O-isopropylidene-D-manno-heptose trimethylene dithioacetal 
• 94530-14-0 6-O-benzyl-5-deoxy-1,2-O-isopropylidene-α-D-xylo-hexofuranose 
• 100-39-0 benzyl bromide 
• 81927-55-1 O-benzyl 2,2,2-trichloroacetimidate 

Relevant academic research and scientific papers

Chemoenzymatic carbon-carbon bond formation leading to non-carbohydrate derivative. Stereoselective synthesis of pentamycin C-11-C-16 fragment

Chemoenzymatic formation of 8 from an aldehyde 5 and dihydroxyacetone phosphate 6 was achieved by the use of fructose 1,6-diphosphate aldolase as a catalyst. Transformation of 8 to 20, corresponding to pentamycin C-11-C-16 fragment, was accomplished via 18a and 18b by chemical processes.