198716-12-0Relevant academic research and scientific papers
1-phenyl-5-amino-4-pyrazole bi-oxadiazole thioether compounds and application thereof
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Paragraph 0018-0020, (2018/04/26)
The invention discloses a preparation method for 1-phenyl-5-amino-4-pyrazole bi-oxadiazole thioether compounds and an application in tobacco mosaic virus resistant activity. The compounds have structures represented by a general formula (I) in the description. The method provided by the invention is based on a 5-amino-1-(3-chloro-2-pyridyl)-4-(5-methylthio-1,3,4-oxadiazole-2-yl)-pyrazole structureand uses ''phenyl'' to replace ''3-chloro-2-pyridyl'' on the 1-position of a pyrazole ring to synthesize a series of the 1-phenyl-5-amino-4-pyrazole bi-oxadiazole thioether compounds, and experimentsof the compounds in vivo show that the compounds have good curative protective and inactivating activity on virus diseases caused by the tobacco mosaic virus (TMV), and the compounds show significanteffects on passivation effects compared with compounds reported in the earlier work of a research group; and the compounds provide an important scientific basis for the research, development, creation of novel pesticides.
Syntheis of Some New Pyrazolotriazines, Pyrazolothiazines and Pyrazolopyrimidines
El-Dean, A. M. Kamal,Geies, A. A.
, p. 2255 - 2269 (2007/10/03)
When the pyrazole derivatives 3a,b were treated with triethyl orthoformate, the pyrazolotriazinethiones 5a,b were obtained.These were S-alkylated to give compounds 6a-d.Treatment of 5a,b with hydrazine hydrate in ethanol afforded 7,8 respectively.Benzylid
