1988-18-7

Usage

InChI:InChI=1/C11H8O2/c12-8-13-11-6-5-9-3-1-2-4-10(9)7-11/h1-8H

Upstream product

• 66-99-9 β-naphthaldehyde 
• 72773-04-7 N-formylbenzotriazole 
• 135-19-3 β-naphthol 
• 25891-31-0 triformylamine 
• 2258-42-6 formyl acetic anhydride 
• 64-18-6 formic acid 
• 108-24-7 acetic anhydride 

Downstream Products

• 135-19-3 β-naphthol 
• 16837-88-0 14-(2-hydroxynaphthyl)-14H-dibenzo[a,j]xanthene 
• 708-06-5 2-hydroxynaphthalene-1-carbaldehyde 

Relevant academic research and scientific papers

Oxidizing agent

PROBLEM TO BE SOLVED: To provide a novel compound useful as an oxidizing agent. SOLUTION: This invention relates to a compound represented by formula (I) [where each symbol is as defined in the specification] and a method for producing the same, and also relates to an oxidizing agent containing the compound. SELECTED DRAWING: None COPYRIGHT: (C)2018,JPOandINPIT

An Isolable and Bench-Stable Epoxidizing Reagent Based on Triazine: Triazox

A new triazine-based oxidizing reagent, 2-hydroperoxy-4,6-diphenyl-1,3,5-triazine (Triazox), has been developed. The reagent can be synthesized from inexpensive starting materials and is a bench-stable solid that is isolable in pure form. Epoxidation of alkenes possessing acid-sensitive functionalities using Triazox proceeded in good to excellent yields. The accompanying nonacidic triazinone coproduct can be easily removed by filtration. These features indicate that Triazox is a practically useful oxidizing reagent.

TiCl4/Et3N-Mediated Condensation of Acetate and Formate Esters: Direct Access to β-Alkoxy- and β-Aryloxyacrylates

A methodology to build (E)-β-alkoxy- and (E)-β-aryloxyacrylate moieties from acetate and formate esters promoted by the TiCl4/Et3N system is presented. The reaction is compatible with a broad range of structural skeletons and elapses through an unusual condensation pathway. Taking into account the obtained results, we propose a plausible mechanism involving a bimetallic titanium intermediate for this type of transformation.

Palladium-Catalyzed Carbonylative Synthesis of Aryl Formates under Mild Conditions

Aryl formates have been extensively applied as CO sources in CO-free carbonylation reactions. However, there are no catalytic synthetic procedures for their preparation. In this manuscript, we developed a convenient palladium-catalyzed procedure for the synthesis of aryl formates. Good yields were achieved under mild reaction conditions with formic acid as the formyl source. A formyl meeting: A convenient palladium-catalyzed carbonylation procedure for the synthesis of aryl formates is developed. Good yields are achieved under mild reaction conditions with formic acid as the formyl source.

Three step procedure for the preparation of aromatic and aliphatic difluoromethyl ethers from phenols and alcohols using a chlorine/fluorine exchange methodology

Difluoromethyl ethers are prepared from phenols in three steps via their respective formate ester derivatives. The formates are first converted to dichloromethyl ethers by treatment with PCl5. These ethers are then induced to undergo chlorine/fluorine exchange to form the respective difluoromethyl ethers. The chlorine/fluorine exchange is carried out by either a room temperature, solvolytic process using THF-5HF or Et3N-3HF as exchange medium, where HF is the ultimate source of fluorine, or by a direct displacement process in sulfolane at 125 C, where KF is the source of fluorine. By one or another of these processes, virtually all phenols, electron-rich and electron-poor, can be converted to their respective difluoromethyl ethers in good yields. Aliphatic alcohols are also able to be converted to their difluoromethyl ether derivatives using the Et3N-3HF exchange medium.

Bi(OTf)3-catalyzed Baeyer-Villiger oxidation of carbonyl compounds with m-CPBA

An efficient method has been developed for the Baeyer-Villiger oxidation of a variety of carbonyl compounds with m-CPBA to afford the corresponding esters/lactones using bismuth triflate as catalyst. The catalyst is reused for Baeyer-Villiger oxidation without significant loss of catalytic activity for three cycles.

Orthoamides, LVI [1]. A new method of wide scope for the preparation of aryl formates

Aryl formates 4a-u, 6, 8, 10, 12, 14, 16, 18, 20, 22, 24, 26 are prepared by formylation of hydroxyarenes 3a-u, 5, 7, 9, 11, 13, 15, 17, 19, 21, 23, 25 with N,N-diformylacetamide (1) or triformamide (2), respectively, in fairly good yields. The reactions can be catalyzed by sodium diformamide or praseodymium(III) triflate. The thiolformate 28 was obtained analogously from 1-thionaphthol (27).

Sc(OTf)3- and TfOH-catalyzed baeyer-villiger oxidation of carbonyl compounds with m-chloroperbenzoic acid

An efficient method for Baeyer-Villiger oxidation of carbonyl compounds to the. corresponding esters/lactones has been developed using m-chloroperbenzoic acid in the presence of a catalytic amount of Sc(OTf)3 or TfOH. Thieme Stuttgart.

N-Formylbenzotriazole: A stable and convenient N- and O-formylating agent

N-Formylbenzotriazole, prepared by the reaction of benzotriazole and formic acid in the presence of dicyclohexylcarbodiimide, is demonstrated to be a superior N- and O-formylating agent.

The Baeyer-Villiger Oxidation of Aromatic Aldehydes and Ketones with Hydrogen Peroxide Catalyzed by Selenium Compounds

A series of organoselenium compounds was investigated as activators of hydrogen peroxide in the Baeyer-Villiger oxidation.As a result, a convenient and cheap method for transformation of aromatic aldehydes, having polycondensed ring systems or electron-donating substituents, and polymethoxy derivatives of acetophenone, into phenols was elaborated.This method utilizes hydrogen peroxide activated by areneseleninic acids, as oxidizing agent.