198992-19-7Relevant academic research and scientific papers
Microscopic acid-base equilibria of a synthetic hydroxamate siderophore analog, piperazine-1,4-bis(N-methylacetohydroxamic acid)
Santos, M. Amelia,Esteves, M. Alexandra,Vaz, M. Candida,Da Silva, J. J. R. Frauesto,Noszal, Bela,Farkas, Etelka
, p. 1977 - 1983 (1997)
The protonation behavior of the cyclic diaminodihydroxamate ligand, piperazine-1,4-bis(N-methyl-acetohydroxamic acid) (H2L1), has been studied at both the macroscopic and the microscopic level. Potentiometric and 1H NMR te
Complexes of cyclic polyaza chelators with cations of alkaline earth metals for enhanced biological activity
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Page/Page column 13, (2010/02/11)
Cyclic polyaza chelators that possess high affinity and specificity for first transition series metal cations exhibit an unanticipated improvement in biological activity when administered as complexes with cations of the alkaline earth metals, Ca(II) and Mg(II), most notably Ca(II). By virtue of this improvement, these complexes are particularly effective in the treatment of pathological conditions, including ischemia and ischemia-reperfusion injury.
