199014-16-9

Basic information

• Product Name: (1-(4-methoxybenzyl)-1H-1,2,4-triazol-5-yl)methanamine
• Synonyms: (1-(4-methoxybenzyl)-1H-1,2,4-triazol-5-yl)methanamine
• CAS NO: 199014-16-9
• Molecular Formula: C₁₁H₁₄N₄O
• Molecular Weight: 218.25506
• Mol File: 199014-16-9.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 424.241°C at 760 mmHg
• Flash Point: 210.374°C
• Appearance: /
• Density: 1.245g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.617
• Storage Temp.: 2-8°C
• CAS DataBase Reference: (1-(4-methoxybenzyl)-1H-1,2,4-triazol-5-yl)methanamine(CAS DataBase Reference)
• NIST Chemistry Reference: (1-(4-methoxybenzyl)-1H-1,2,4-triazol-5-yl)methanamine(199014-16-9)
• EPA Substance Registry System: (1-(4-methoxybenzyl)-1H-1,2,4-triazol-5-yl)methanamine(199014-16-9)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 199014-16-9(Hazardous Substances Data)

Usage

Description

(1-(4-methoxybenzyl)-1H-1,2,4-triazol-5-yl)methanamine is a triazole derivative chemical compound characterized by a triazole ring, a methanamine group, and a 4-methoxybenzyl substituent. It has been investigated for its potential pharmaceutical properties, such as antifungal and antimicrobial activities, and may also be utilized in agricultural chemicals as a pesticide. The 4-methoxybenzyl group is believed to enhance its biological activities and pharmacokinetics, with ongoing research to explore its full spectrum of properties and applications.

Uses

Used in Pharmaceutical Industry:
(1-(4-methoxybenzyl)-1H-1,2,4-triazol-5-yl)methanamine is used as an active pharmaceutical ingredient for its antifungal and antimicrobial properties, offering potential treatments for various infections caused by fungi and bacteria.
Used in Agricultural Chemicals Industry:
In the agricultural sector, (1-(4-methoxybenzyl)-1H-1,2,4-triazol-5-yl)methanamine is used as a potential pesticide, leveraging its antimicrobial properties to protect crops from harmful microorganisms and pests, thereby enhancing crop yield and quality.

InChI:InChI=1/C11H14N4O/c1-16-10-4-2-9(3-5-10)7-15-11(6-12)13-8-14-15/h2-5,8H,6-7,12H2,1H3

Upstream product

• 199014-14-7 5-(hydroxymethyl)-1-(4-methoxybenzyl)-1,2,4-triazole 
• 824-94-2 p-methoxybenzyl chloride 
• 115201-42-8 1-(4-Methoxybenzyl)-1,2,4-triazole 
• 199014-15-8 5-(phthalimidomethyl)-1-(4-methoxybenzyl)-1,2,4-triazole 
• 100-39-0 benzyl bromide 

Downstream Products

• 199014-20-5 6-amino-2-<2-(4-methoxybenzyl)-2H-<1,2,4>triazol-3-ylmethyl>-1,2,3,4-tetrahydro-isoquinoline 
• 199014-17-0 2-<2-(4-methoxybenzyl)-2H-<1,2,4>triazol-3-ylmethyl>-6-nitro-1,2,3,4-tetrahydro-isoquinoline 

Relevant articles and documents

Process and intermediates for preparing 4'-trifluoromethylbiphenyl-2-carboxylic acid [2-(2H-[1,2,4]triazol-3-ylmethyl)-1,2,3,4-tetrahydro-isoquinolin-6-yl]-a mide

A process for preparing the compound of formula (1) is disclosed. STR1 The starting materials are an N-triazolylmethyl-6-aminoisoquinoline and a 4-biphenyl-2-carboxylic acid derivative.

Tandem reduction studies of bromo compounds using tetrabutylammonium borohydride

Tetrabutylammonium borohydride can be used for multifunctional transformations through tandem reductions of halo compounds in THF.