199014-20-5

Upstream product

• 199014-15-8 5-(phthalimidomethyl)-1-(4-methoxybenzyl)-1,2,4-triazole 
• 199014-14-7 5-(hydroxymethyl)-1-(4-methoxybenzyl)-1,2,4-triazole 
• 199014-16-9 5-(aminomethyl)-1-(4-methoxybenzyl)-1,2,4-triazole 
• 199014-22-7 [2-[2-[(methylsulfonyl)oxy]ethyl]-4-nitrophenyl]methyl methanesulfonate 
• 186390-74-9 2-(2-Hydroxymethyl-5-nitro-phenyl)-ethanol 
• 824-94-2 p-methoxybenzyl chloride 
• 115201-42-8 1-(4-Methoxybenzyl)-1,2,4-triazole 
• 199014-17-0 2-<2-(4-methoxybenzyl)-2H-<1,2,4>triazol-3-ylmethyl>-6-nitro-1,2,3,4-tetrahydro-isoquinoline 

Relevant academic research and scientific papers

An efficient synthesis of 6-substituted 2-(2H-[1,2,4]triazol-3- ylmethyl)-1,2,3,4-tetrahydro-isoquinolines

A synthesis of 6-nitro and 6-amino 2-(2H-[1,2,4]triazol-3- ylmethyl)1,2,3,4-tetrahydro-isoquinolines using a bis-alkylation process is described. 5-(Aminomethyl)-1-(p-methoxybenzyl)-triazole was prepared by a regioselective route from 1,2,4-triazole.

Process and intermediates for preparing 4'-trifluoromethylbiphenyl-2-carboxylic acid [2-(2H-[1,2,4]triazol-3-ylmethyl)-1,2,3,4-tetrahydro-isoquinolin-6-yl]-a mide

A process for preparing the compound of formula (1) is disclosed. STR1 The starting materials are an N-triazolylmethyl-6-aminoisoquinoline and a 4-biphenyl-2-carboxylic acid derivative.