199014-22-7

Usage

Uses

Used in Organic Synthesis:
2-(2-(Methylsulfonyloxy)ethyl)-4-nitrobenzyl (Methanesulfonate) is used as a protecting group in organic synthesis for [application reason] to facilitate the selective reactions of functional groups in complex molecules.
Used in Peptide Synthesis:
In the pharmaceutical industry, 2-(2-(Methylsulfonyloxy)ethyl)-4-nitrobenzyl (Methanesulfonate) is used as a reagent in peptide synthesis for [application reason] to protect the functional groups of amino acids, allowing for the stepwise assembly of peptide chains.
Used as a Precursor in Pharmaceutical and Agrochemical Compounds:
2-(2-(Methylsulfonyloxy)ethyl)-4-nitrobenzyl (Methanesulfonate) is used as a precursor in the synthesis of various pharmaceutical and agrochemical compounds for [application reason] to provide a versatile intermediate for the development of new drugs and agrochemicals.
Used in Research and Industrial Settings:
Due to its versatility in organic synthesis, 2-(2-(Methylsulfonyloxy)ethyl)-4-nitrobenzyl (Methanesulfonate) is widely used in both research and industrial settings for [application reason] to enable the development of novel chemical entities and improve the efficiency of existing synthetic routes.

Upstream product

• 124-63-0 methanesulfonyl chloride 
• 186390-74-9 2-(2-Hydroxymethyl-5-nitro-phenyl)-ethanol 
• 1025823-76-0 2-(2-Carboxy-5-nitro-phenyl)-malonic acid 
• 39585-32-5 2-carboxymethyl-4-nitro-benzoic acid 
• 99-60-5 2-chloro-4-nitrobenzoic acid 
• 186390-71-6 2-(carboxy-5-nitro-phenyl)malonic acid dimethyl ester 

Downstream Products

• 1132943-59-9 1-(3-tert-butyl-4-methoxy-5-(6-nitro-3,4-dihydroisoquinolin-2(1H)-yl)phenyl)pyrimidine-2,4(1H,3H)-dione 
• 199014-20-5 6-amino-2-<2-(4-methoxybenzyl)-2H-<1,2,4>triazol-3-ylmethyl>-1,2,3,4-tetrahydro-isoquinoline 
• 186390-77-2 6-nitro-1,2,3,4-tetrahydro-isoquinoline 
• 199014-17-0 2-<2-(4-methoxybenzyl)-2H-<1,2,4>triazol-3-ylmethyl>-6-nitro-1,2,3,4-tetrahydro-isoquinoline 

Relevant academic research and scientific papers

BICYCLOANILINE DERIVATIVE

The invention relates to a compound of a general formula (I): wherein A1 and A2 each mean a nitrogen atom or an optionally-substituted methine group; Ring B means a 5-membered to 7-membered aliphatic ring, or a spiro or bicyclo ring formed from the aliphatic ring and any other 3-membered to 7-membered aliphatic ring; R1 means a hydrogen atom, or an optionally-substituted C1-C6 alkyl group, or an optionally-substituted aryl, aralkyl or heteroaryl group; R2 means an optionally-substituted aryl, aralkyl or heteroaryl group; and X means a group of =NH or =O, etc. Based on its excellent Wee1 kinase-inhibitory effect, the compound of the invention has cell growth-inhibitory effect and has an additive/synergistic effect with any other anticancer agent, and is therefore useful in the field of medicine.

Oxazolidinones having a benzannulated 6- or 7-membered heterocycle

The present invention provides oxazolidinones having a benzannelated 6- or 7-membered heterocycle as antibacterial agents.

An efficient synthesis of 6-substituted 2-(2H-[1,2,4]triazol-3- ylmethyl)-1,2,3,4-tetrahydro-isoquinolines

A synthesis of 6-nitro and 6-amino 2-(2H-[1,2,4]triazol-3- ylmethyl)1,2,3,4-tetrahydro-isoquinolines using a bis-alkylation process is described. 5-(Aminomethyl)-1-(p-methoxybenzyl)-triazole was prepared by a regioselective route from 1,2,4-triazole.