199119-46-5

Basic information

• Product Name: N-im-Trityl-D-histidine
• Synonyms: H-D-His(tau-Trt)-OH;1-(Triphenylmethyl)-D-histidine;(2R)-2-AMMonio-3-(1-trityl-1H-iMidazol-4-yl)propanoate;Arg(Pbf);(R)-2-AMino-3-(1-trityl-1H-iMidazol-4-yl)propanoic acid;D-His(Trt)-OH;Nim-Trityl-D-histidine≥ 99% (HPLC)
• CAS NO: 199119-46-5
• Molecular Formula: C25H23N3O2
• Molecular Weight: 397.48
• Mol File: 199119-46-5.mol
• Article Data: 8

Chemical Properties

• Boiling Point: 584.8oC at 760 mmHg
• Flash Point: 307.5oC
• Appearance: /
• Density: 1.19
• Storage Temp.: 2-8°C
• PKA: 1.78±0.10(Predicted)
• CAS DataBase Reference: N-im-Trityl-D-histidine(CAS DataBase Reference)
• NIST Chemistry Reference: N-im-Trityl-D-histidine(199119-46-5)
• EPA Substance Registry System: N-im-Trityl-D-histidine(199119-46-5)

Safety Data

• Hazardous Substances Data: 199119-46-5(Hazardous Substances Data)

Usage

Chemical Properties

White to off-white powder

Uses

Nim-Trityl-D-histidine is used as a reagent in solid-phase synthesis and screening of peptides as catalysts for asymmetric induction of desymmetrization of bis(phenol)s.

Upstream product

• 75-77-4 chloro-trimethyl-silane 
• 95383-91-8 L-Histidine 
• 76-83-5 trityl chloride 
• 74853-62-6 N^α,N^im-ditritylhistidine 
• 71-00-1 L-histidine 
• 71-00-1 L-histidine 
• 109425-51-6 Fmoc-His(Trt)-OH 
• 32946-53-5 N^im-trityl-L-histidine hydrochloride 
• 75-78-5 dimethylsilicon dichloride 

Downstream Products

• 1333228-14-0 [{[(S)-1-Methylcarbamoyl-2-(1-trityl-1H-imidazol-4-yl)-ethylcarbamoyl]-methyl}-(3-phenyl-propyl)-amino]-acetic acid methyl ester 
• 1333228-00-4 C₂₆H₂₆N₄O*CH₂O₂ 

Relevant articles and documents

Self-healing response in supramolecular polymers based on reversible zinc-histidine interactions

Histidine-metal interactions are utilized in many biological materials as reinforcing crosslinks, and in particular, are believed to contribute as reversible crosslinks to the intrinsic self-recovery behavior of mussel byssal threads. In this contribution

PYRROLOBENZODIAZEPINE DIMER PRECURSOR AND LIGAND-LINKER CONJUGATE COMPOUND THEREOF

The present invention relates to a pyrrolobenzodiazepine dimer prodrug and a ligand-linker conjugate compound thereof, a composition containing these, and therapeutic use thereof particularly as an anticancer drug. The stability of the compounds themselves and the stability thereof in plasma are excellent and the compounds are advantageous in terms of manifestation of toxicity, and thus the compounds are industrially useful in that it is possible to target proliferative diseases such as cancer, to perform a specific treatment, to maximize the drug efficacy, and to minimize the occurrence of side effects.

DIARYLSULPHID BACKBONE CONTAINING PHOTOLABILE PROTECTING GROUPS

The present invention relates to photoactivable protecting groups containing a diarylsulphid chromophore, a method for the synthesis thereof and their use as photoactivable protecting groups using maskless photolithography based array synthesis. wherein R2 is [Formula II] or wherein R2 is [Formula III] or [Formula IV] wherein R7 is a natural amino acid, a non-natural amino acid or an amino acid derivative forming an urethan bond to formula Ib, or wherein formula IV represents the carboxy function of a natural amino acid, a non-natural amino acid or an amino acid derivative, forming an ester bond to formula Ib.