199182-33-7Relevant academic research and scientific papers
Chiral resolution through stereoselective transglycosylation by sucrose phosphorylase: Application to the synthesis of a new biomimetic compatible solute, (R)-2-O-α-d-glucopyranosyl glyceric acid amide
Wildberger, Patricia,Brecker, Lothar,Nidetzky, Bernd
, p. 436 - 438 (2014)
Sucrose phosphorylase catalysed glycosylation of glyceric acid amide with complete regio- and diastereo-selectivity is studied. (R)-2-O-α-d- Glucopyranosyl glyceric acid amide was obtained in high yield from single-step transformation of racemic glyceric acid amide and sucrose. Non-productive binding of (S)-glyceric acid amide appeared to underlie strict enantiodiscrimination by the enzyme, thus supporting chiral resolutions based on stereoselective transglycosylation.
