199275-88-2Relevant academic research and scientific papers
1,4,8,11-Tetraazabicyclo[9.3.1]pentadecanes: Synthesis and Use of a New Strategy for the Selective cis -N4,N8-Difunctionalization of Cyclam Derivatives
Guilard, Roger,Bessmertnykh, Alla G.,Beletskaya, Irina P.
, p. 1190 - 1192 (1997)
A new efficient route to derivatives of 1,4,8,11-tetraazabicyclo[9.3.1]pentadecane 2 and their use in a procedure of selective N4,N8-difunctionalization of cyclam is reported.
New macrocyclic ligands. XIII single-ring and tri-linked macrocyclic systems derived from selectively protected cyclam
Dong,Lindoy
, p. 291 - 297 (2007/10/03)
The synthesis of the four single-ring cyclam derivatives together with the related tri-linked ring derivatives and tetrabenzylated derivative was reported. In the synthesis, differential Boc-protected cyclam derivatives were used as key intermediates. Benzylated and tri-linked cyclam products were found to rely heavily on high-resolution mass spectrometry (HRMS) and all compounds yielded satisfactory HRMS data.
