19936-22-2

Upstream product

• 85689-77-6 1-(4-cyclopentylphenyl)ethan-1-one 
• 827-55-4 p-cyclopentyltoluene 
• 700-88-9 cyclopentylbenzene 
• 71-43-2 benzene 
• 106-37-6 1.4-dibromobenzene 
• 59247-47-1 tert-butyl-4-bromobenzoate 
• 586-76-5 4-Bromobenzoic acid 
• 120-92-3 cyclopentanone 
• 19936-20-0 4-(cyclopent-1-en-1-yl)benzonitrile 
• 6725-74-2 1-bromo-4-(cyclopent-1-en-1-yl)benzene 
• 137-43-9 Cyclopentyl bromide 
• 124-38-9 carbon dioxide 
• 19936-21-1 4-cyclopent-1-enyl-benzoic acid 

Downstream Products

• 160598-47-0 Methyl 4-cyclopentylbenzoate 
• 171623-29-3 (4-cyclopentylphenyl)methanol 
• 40452-70-8 4-Cyclopentylbenzaldehyde 

Relevant academic research and scientific papers

Modulators of methyl modifying enzymes, compositions and uses thereof

Agents for modulating methyl modifying enzymes, compositions and uses thereof are provided herein.

MODULATORS OF METHYL MODIFYING ENZYMES, COMPOSITIONS AND USES THEREOF

Agents for modulating methyl modifying enzymes, compositions and uses thereof are provided herein

NOVEL MCH RECEPTOR ANTAGONISTS

The present invention relates to a melanin concentrating hormone antagonist compound of formula (I); wherein Ar1, L1, R1, q, X, R2, R3, R4, and R5 are as defined, or a pharmaceutically acceptable salt, solvate, or enantiomer thereof useful in the treatment, prevention or amelioration of symptoms associated with obesity and related diseases.

Discovery of potent 3,5-diphenyl-1,2,4-oxadiazole sphingosine-1-phosphate-1 (S1P1) receptor agonists with exceptional selectivity against S1P2 and S1P3

A class of 3,5-diphenyl-1,2,4-oxadiazole based compounds have been identified as potent sphingosine-1-phosphate-1 (S1P1) receptor agonists with minimal affinity for the S1P2 and S1P3 receptor subtypes. Analogue 26 (S1P1 IC50 = 0.6 nM) has an excellent pharmacokinetics profile in the rat and dog and is efficacious in a rat skin transplant model, indicating that S1P3 receptor agonism is not a component of immunosuppressive efficacy.

SYNTHESIS OF p-ALKYLBENZOIC ACIDS BY ONE-ELECTRON OXIDATION OF p-ALKYLTOLUENES. MINDO/3 CALCULATIONS OF p-ALKYLTOLUENES AND THEIR RADICAL CATIONS

Calculations for p-cymene, p-cyclopropyltoluene, and their radical cations were undertaken by the LCAO-MO SCF method in the MINDO/3 valence approximation.It was shown that the radical-cations are stabilized by ?,? conjugation of the methyl group.The radical-cations are hardly stabilized at all by the p-sec-alkyl radicals.This leads to the result that the oxidation of p-sec-alkyltoluenes and p-cycloalkyltoluenes through electron transfer only takes place at the methyl group with the formation of p-sec-alkyl- and p-cycloalkylbenzoic acids.

Properties of the Liquid Crystals Formed by Ceratin Azomethines Derived from 4-Cycloalkylanilines and from 4-Cycloalkylbenzaldehydes

The liquid crystal behaviour of four homologous series of azomethines related to the nO.m series but containing a cycloalkyl group, is reported and discussed.Many of these compounds show extensive smectic polymorphism, one member of the nO.c6 series giving rise to five smectic polymorphic modofications for which phase type assignments have been made by thermal optical microscopy.Keywords: smectic polymorphism, azomethines, cycloalkyl derivatives