40452-70-8

Usage

Uses

Used in Perfumery:
P-cyclopentylbenzaldehyde is used as a fragrance ingredient for its fresh, sweet scent, enhancing the aroma of various consumer products.
Used in Food Industry:
In the food industry, p-cyclopentylbenzaldehyde is used as a flavoring agent to impart a pleasant taste to different food items.
Used in Pharmaceutical Industry:
P-cyclopentylbenzaldehyde is utilized as a key intermediate in the synthesis of complex organic molecules, contributing to the development of new pharmaceuticals.
Used in Agrochemical Industry:
p-cyclopentylbenzaldehyde is also employed in the production of agrochemicals, where it serves as a precursor for the synthesis of various agrochemical products.
Used in Chemical Industry:
P-cyclopentylbenzaldehyde is used as a precursor in the manufacture of UV absorbers, dyes, and other specialty chemicals, highlighting its importance in the chemical industry.

InChI:InChI=1/C12H14O/c13-9-10-5-7-12(8-6-10)11-3-1-2-4-11/h5-9,11H,1-4H2

Upstream product

• 74598-76-8 N-[1-(4-Cyclopentyl-phenyl)-meth-(E)-ylidene]-N'-(2,4-dinitro-phenyl)-hydrazine 
• 201230-82-2 carbon monoxide 
• 142-29-0 cyclopentene 
• 71-43-2 benzene 
• 171623-29-3 (4-cyclopentylphenyl)methanol 
• 122-51-0 orthoformic acid triethyl ester 
• 137-43-9 Cyclopentyl bromide 
• 700-88-9 cyclopentylbenzene 
• 1122-91-4 4-bromo-benzaldehyde 
• 287944-10-9 2-cyclopent-1-enyl-4,4,5,5-tetramethyl-[1,3,2]dioxaborolane 
• 915016-86-3 1-(p-formylphenyl)cyclopentene 
• 104-88-1 4-chlorobenzaldehyde 
• 827-52-1 1-phenyl-1-cyclohexane 
• 85689-77-6 1-(4-cyclopentylphenyl)ethan-1-one 

Downstream Products

• 1518-83-8 4-cyclopentylphenol 
• 13081-30-6 2-chloro-4-cyclopentylphenol 
• 860616-45-1 1-(3-bromo-propoxy)-2-chloro-4-cyclopentyl-benzene 

Relevant academic research and scientific papers

COMPOUNDS AND METHOD OF USE

This present disclosure relates to compounds with ferroptosis inducing activity, a method of treating a subject with cancer with the compounds, and combination treatments with a second therapeutic agent.

Mild negishi cross-coupling reactions catalyzed by acenaphthoimidazolylidene palladium complexes at low catalyst loadings

Considering that the strong σ-donor property of ylidenes derived from π-extended imidazolium salts is conducive to increasing the catalytic activity of the resulting palladium N-heterocyclic carbene complexes, robust acenaphthoimidazol-ylidene palladium complexes 3a-c with varying bulky substituted groups were prepared from the corresponding acenaphthoimidazolium chlorides by heating with PdCl2 and K2CO3 in neat 3-chloropyridine in satisfactory yields. Even at a catalyst loading as low as 0.25 mol %, complex 3a exhibited extremely high catalytic activity toward Negishi cross-coupling of alkylzinc reagents with a wide range of (hetero)aryl halides under mild reaction conditions within 30 min. Besides a great number of bromoarenes, various less expensive and inactive (hetero)aryl chlorides were coupled successfully with the alkyl- and arylzinc reagents, in which active functional groups (such as -NH2) were well tolerated even in one-pot dicoupling transformations without protection. In addition, in the case of coupling with secondary alkylzinc reagents, undesired β-hydride elimination leading to isomerized linear products was efficaciously suppressed. The catalyst system also displayed superiority in the construction of heterobiaryls through the coupling of heteroarylzinc reagents and heterocylic chloroarenes which were hardly accessible from the corresponding organoboron reagents by Suzuki-coupling reactions. Therefore, the protocol described in this paper represents a mild, general, and scalable approach to access various structurally intriguing and functionalized (hetero)aryls.

Synthesis of Certain Mesogenic Azomethines Derived from 4-Cycloalkylanilines and from 4-Cycloalkylbenzaldehydes

General procedures are described for the synthesis of members of five pairs of related homologous series of mesogenic azomethines differing in the mode of linkage of the CH=N group and containing a cycloalkyl group in a terminal position.

Properties of the Liquid Crystals Formed by Ceratin Azomethines Derived from 4-Cycloalkylanilines and from 4-Cycloalkylbenzaldehydes

The liquid crystal behaviour of four homologous series of azomethines related to the nO.m series but containing a cycloalkyl group, is reported and discussed.Many of these compounds show extensive smectic polymorphism, one member of the nO.c6 series giving rise to five smectic polymorphic modofications for which phase type assignments have been made by thermal optical microscopy.Keywords: smectic polymorphism, azomethines, cycloalkyl derivatives

Formylation and Acylation Reactions Catalysed by Trifluoromethanesulphonic Acid

Regioselective formylation of toluene, m- and p-xylene, and mesitylene has been achieved by carbonylation in trifluoromethanesulphonic acid at CO pressures of 90-125 atm.In the case of cumene, the formylation reaction is in competition with disproportionation to form di- and tri-isopropylbenzenes, leading to a complex product mixture.Slow addition of cyclohexene or cyclopentene to a mixture of benzene and CF3SO3H under a high CO pressure affords 4-cyclohexylbenzaldehyde and 4-cyclopentylbenzaldehyde in 34percent and 33percent yieds, respectively, while 2-methylbut-1-ene gives 2,2,3-trimethylindanone (39percent) under similar conditions.When cyclohexene is mixed with the acid under carbon monoxide (120 atm) before addition of benzene the major products are cyclohexyl phenyl ketone and cyclohexenyl cyclohexyl ketones.