19942-80-4

Upstream product

• 64554-57-0 bis([1,1′-biphenyl]-4-yl) sulfide 
• 80-07-9 4,4'-dichlorodiphenyl sulphone 
• 98-80-6 phenylboronic acid 
• 80-09-1 4,4'-sulfonediphenol 
• 1623-93-4 4-diphenylsulfonyl chloride 
• 67-64-1 acetone 
• 92-52-4 biphenyl 
• 91815-47-3 4,4″-sulfinyldi-1,1′-biphenyl 

Downstream Products

• 144432-80-4 2-(biphenyl-4-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane 

Relevant academic research and scientific papers

Palladium catalyzed coupling of aryl chlorides with arylboronic acids

Aryl chlorides bearing electron withdrawing groups were successfully coupled with arylboronic acids (Suzuki reaction). Two palladium catalyst ligands, tricyclohexylphosphine (PCy3) and 1,3-bis(diphenylphosphino)propane (dppp), were found to be superior in catalyzing the reaction.

Palladium-catalyzed, ligand-free Suzuki reaction in water using aryl fluorosulfates

Aryl fluorosulfates were prepared by a simple method and employed as coupling partners in the Suzuki-Miyaura reaction. The cross-coupling reactions were performed in water under air at room temperature without ligands or additives such as surfactants or phase-transfer reagents and proceeded smoothly to give excellent yields. Aryl fluorosulfates could also be used as alternatives to halides or triflates in other coupling reactions.