199468-81-0

Basic information

• Product Name: (2S,3S)-2-azido-3-phenylisohexanoic acid
• Synonyms: (2S,3S)-2-azido-3-phenylisohexanoic acid
• CAS NO: 199468-81-0
• Molecular Weight: 233.27
• Mol File: 199468-81-0.mol

Chemical Properties

• CAS DataBase Reference: (2S,3S)-2-azido-3-phenylisohexanoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: (2S,3S)-2-azido-3-phenylisohexanoic acid(199468-81-0)
• EPA Substance Registry System: (2S,3S)-2-azido-3-phenylisohexanoic acid(199468-81-0)

Safety Data

• Hazardous Substances Data: 199468-81-0(Hazardous Substances Data)

Upstream product

• 1775-44-6 (2E)-4-methylpent-2-enoic acid 
• 100-58-3 phenylmagnesium bromide 
• 51690-50-7 4-methyl-3-phenylpentanoic acid 
• 611-70-1 phenyl isopropyl ketone 
• 176198-10-0 (4R,3'S)-4-phenyl-3-(3'-phenylisohexanyl)-2-oxazolidinone 
• 184784-56-3 N-(4'-methyl-2'-pentenoyl)-4S-phenyl-1,3-oxazolidin-2-one 
• 176018-91-0 (S)-3-((S)-4-Methyl-3-phenyl-pentanoyl)-4-phenyl-oxazolidin-2-one 
• 199468-78-5 (S)-3-((2S,3S)-2-Azido-4-methyl-3-phenyl-pentanoyl)-4-phenyl-oxazolidin-2-one 
• 77921-03-0 (E)-4-methyl-3-phenyl-2-pentenoic acid 

Relevant articles and documents

Synthesis and conformational features of topographically constrained designer chimeric amino adds: The β-isopropyl phenylalanines

All four optically pure isomers of the highly conformationally constrained novel chimeric amino acid, β-isopropylphenylalanine or β- phenylleucine, were asymmetrically synthesized in five to six steps in 20 - 25% overall yield. Computer-assisted molecular modeling revealed that the β- isopropyl group in these chimeric amino acids plays the dominant role in determining the most favorable side chain conformations.

Asymmetric synthesis of optically pure β-isopropylphenylalanine: A new β-branched unusual amino acid

All four optically pure isomers of a highly conformationally constrained unusual amino acid, β-isopropylphenylalanine, have been asymmetrically synthesized.