19948-27-7

Usage

Uses

Used in Pharmaceutical Research and Development:
1-Methyl-3-hydroxysuccinimide is used as a reagent for the synthesis of various bioactive molecules and pharmaceutical intermediates, contributing to the development of new drugs and therapeutic agents.
Used in Protein and Peptide Modification:
1-Methyl-3-hydroxysuccinimide is utilized as a modifying agent for proteins and peptides, allowing for the enhancement of their properties and functionalities in biological systems.
Used in Drug Conjugation:
1-METHYL-3-HYDROXYSUCCINIMIDE is employed as a coupling agent in the production of protein conjugates, which are essential for the creation of antibody-drug conjugates and other targeted drug delivery systems, improving the specificity and efficacy of treatments.
Used in Organic Synthesis:
1-Methyl-3-hydroxysuccinimide is used as a key component in organic synthesis processes, facilitating the formation of complex molecular structures and contributing to the advancement of chemical research.
It is crucial to handle 1-methyl-3-hydroxysuccinimide with care and follow safety protocols to mitigate any potential hazards associated with its use.

InChI:InChI=1/C5H7NO3/c1-6-4(8)2-3(7)5(6)9/h3,7H,2H2,1H3

Upstream product

• 617-48-1 malic acid 
• 74-89-5 methylamine 

Downstream Products

• 13220-33-2 1-methyl-3-pyrrolidinol 

Relevant academic research and scientific papers

Preparation method of 1-methyl-3-pyrrolidinol

The invention relates to the technical field of synthesis of medical intermediates, and particularly discloses a preparation method of 1-methyl-3-pyrrolidinol. The preparation method comprises the following steps that S1, a compound I and a compound II are subjected to a ring closing reaction, so a compound III is obtained; and S2, the compound III obtained in the step S1 and a reducing agent IV are subjected to a reduction reaction, so 1-methyl-3-pyrrolidinol is obtained, wherein the compound I, the compound II and the compound III are as shown in the specification; and the reducing agent IV is one or more selected from a group consisting of sodium borohydride, potassium borohydride, boron trifluoride-diethyl ether and boron tribromide-diethyl ether. According to the preparation method, the compound II and the compound I are selected and subjected to the ring closing reaction to obtain the intermediate compound III, and the compound III is solid and is easy to crystallize and purify, so the purification difficulty of the intermediate is reduced, the purity of the intermediate is favorably improved, and the product quality of the 1-methyl-3-pyrrolidinol is further improved.

Isothiazolecarboxylic acid derivatives and their use as microbicides

Novel isothiazolecarboxylic acid derivatives of the formula (I), in which A, Q, Z and k have the meanings mentioned in the specification, processes for the preparation of the new compounds and their use as microbicides.