19950-82-4

Upstream product

• 23249-97-0 4-(2'-benzimidazolyl)propionic acid 
• 108-24-7 acetic anhydride 
• 1018-52-6 N-(2-azidophenyl)succinimide 
• 1012-81-3 N-<2-aminophenyl>-2,5-pyrrolidinedione 
• 5838-57-3 2-(but-3-en-1-yl)-1H-benzo[d]imidazole 
• 137076-20-1 2,3-dihydro-1-hydroxy-1H-pyrrolo-[1,2-a]benzimidazole 
• 83549-10-4 o-aminosuccinanilic acid 
• 95-54-5 1,2-diamino-benzene 

Downstream Products

• 103706-53-2 (E)-3-(1H-Benzoimidazol-2-yl)-4-(2-hydroxy-phenyl)-but-3-enoic acid 
• 103706-55-4 (E)-3-(1H-Benzoimidazol-2-yl)-4-(4-formyl-phenyl)-but-3-enoic acid 
• 103706-57-6 (E)-3-(1H-Benzoimidazol-2-yl)-4-(4-chloro-phenyl)-but-3-enoic acid 
• 103706-52-1 (E)-3-(1H-Benzoimidazol-2-yl)-4-(4-hydroxy-phenyl)-but-3-enoic acid 
• 103706-54-3 (E)-3-(1H-Benzoimidazol-2-yl)-4-(3-hydroxy-phenyl)-but-3-enoic acid 
• 103706-58-7 3-(1H-benzimidazole-2)3-benzylidene propanoic acid methylester 
• 103706-51-0 (E)-3-(1H-Benzoimidazol-2-yl)-4-phenyl-but-3-enoic acid 
• 103720-95-2 3-(1H-benzimidazole-2)3-benzylpropanoic Acid 
• 103706-43-0 3-[1-Phenyl-meth-(E)-ylidene]-2,3-dihydro-benzo[d]pyrrolo[1,2-a]imidazol-1-one 
• 103706-47-4 4-[1-Oxo-1,2-dihydro-benzo[d]pyrrolo[1,2-a]imidazol-(3E)-ylidenemethyl]-benzaldehyde 
• 103706-50-9 3-[1-(4-Chloro-phenyl)-meth-(E)-ylidene]-2,3-dihydro-benzo[d]pyrrolo[1,2-a]imidazol-1-one 
• 103706-46-3 Acetic acid 3-[1-oxo-1,2-dihydro-benzo[d]pyrrolo[1,2-a]imidazol-(3E)-ylidenemethyl]-phenyl ester 
• 103706-45-2 Acetic acid 2-[1-oxo-1,2-dihydro-benzo[d]pyrrolo[1,2-a]imidazol-(3E)-ylidenemethyl]-phenyl ester 
• 103706-44-1 Acetic acid 4-[1-oxo-1,2-dihydro-benzo[d]pyrrolo[1,2-a]imidazol-(3E)-ylidenemethyl]-phenyl ester 

Relevant academic research and scientific papers

Functionalized orthoesters as powerful building blocks for the efficient preparation of heteroaromatic bicycles

By combining substituted anilines with functionalized orthoesters, an efficient and connective methodology for the preparation of benzoxazole, benzothiazole, and benzimidazole derivatives has been established. The versatility of this approach enables the development of new libraries of heterocycles containing multifunctional sites.

TRICYCLIC-CYCLIC AMINES AS NOVEL CHOLINESTERASE INHIBITORS

Compounds of the formula wherein ring A, ring B, ring D, R2, R3, R4 R5, R6, R11, R12, R13, E, G, X and P are as defined below. The compounds of formula I are cholinesterase inhibitors and are useful in enhancing memory in patients suffering from dementia and Alzheimer's disease.

Spectroscopic Studies of Benzimidazole, Quinoxaline and Quinoline Derivatives.

Four fused benzimidazoles, two quinoxalines and two fused quinoline derivatives were studied with respect to their MS, NMR and IR spectra.These compounds were chosen in order to compare the effect of the size of the hetero ring and the presence of C=N and C=O on their spectral behavior.

APPLICATION OF PHOSPHORUS, ARSENIC AND ANTIMONY REAGENTS IN THE SYNTHESIS OF HETEROCYCLIC COMPOUNDS

The ability of different reagents of the type R3XBr2, where R are various alkyl, alkoxide, phenyl, and phenoxide groups, and X is P, As and Sb, to promote an intramolecular cyclization of suitably substituted aromatic diamines has been investigated.The type of R group and X was found to have a great influence on the ability of these reagents to promote this type of cyclization.Best results were obtained when R=OMe and X=P. Key words: Phosphorus; arsenic; antimony; dibromotriphenylphosphorane; diamines; heterocycles.

HETEROCYCLES BY INTRAMOLECULAR AZA-WITTIG REACTIONS OF IMINOPHOSPHORANES OBTAINED FROM 2-AZIDOBENZOYL- AND 2-AZIDOBENZYLIDENE DERIVATIVES

Iminophosphoranes have been used in intramolecular aza-Wittig reactions to prepare pyrrolobenzimidazoles, fused quinazolines, quinolines, and an isoindolobenzotriazepinone.

Dibromotriphenylphosphorane Promoted Synthesis of Condensed Heterocyclic Systems from Aromatic Diamines

A new and rather widely applicable method for the synthesis of a number of tri, tetra-, and pentacyclic compounds from ortho-aminodiacylarylimides and dibromotriphenylphosphorane via an intramolecular cyclization is reported.A mechanism for this cyclizati