19953-58-3

Basic information

• Product Name: CLA
• Synonyms: CYPRIDINA LUCIFERIN ANALOGUE;CLA-PHENYL;CLA;2-METHYL-6-PHENYL-3,7-DIHYDROIMIDAZO[1,2-A]PYRAZIN-3(7H)-ONE;2-METHYL-6-PHENYL-3,7-DIHYDROIMIDAZO[1,2-A]PYRAZIN-3-ONE;CYPRIDINA LUCIFERIN;CLA [CHEMILUMINESCENCE REAGENT];2-Methyl-3(7H)-oxo-6-phenylimidazo[1,2-a]pyrazine
• CAS NO: 19953-58-3
• Molecular Formula: C₁₃H₁₁N₃O
• Molecular Weight: 225.25
• Product Categories: Cypridina Luciferin Analog;Analytical Chemistry;Chemiluminescence
• Mol File: 19953-58-3.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• Storage Temp.: Refrigerator
• CAS DataBase Reference: CLA(CAS DataBase Reference)
• NIST Chemistry Reference: CLA(19953-58-3)
• EPA Substance Registry System: CLA(19953-58-3)

Safety Data

• Hazardous Substances Data: 19953-58-3(Hazardous Substances Data)

Usage

General Description

2-Methyl-6-phenyl-3,7-dihydroimidazo[1,2-a]pyrazin-3-one is a chemical compound belonging to the class of imidazo[1,2-a]pyrazin-3-one derivatives. It contains a 2-methyl-6-phenyl substitution on the imidazo[1,2-a]pyrazin-3-one core structure. 2-Methyl-6-phenyl-3,7-dihydroimidazo[1,2-a]pyrazin-3-one has potential pharmaceutical importance due to its diverse biological activities, including antiviral, antifungal, and anticancer properties. It is also being studied for its potential use as a central nervous system depressant and anxiolytic. Additionally, its unique structure makes it an interesting target for medicinal chemistry research aimed at developing novel therapeutic agents.

Upstream product

• 13535-13-2 2-amino-5-phenylpyrazine 
• 78-98-8 2-oxopropanal 

Downstream Products

• 19953-59-4 3-acetamido-6-phenylpyrazine 

Relevant articles and documents

Influence of electron-donating and electron-withdrawing substituents on the Chemiluminescence behavior of Coelenterazine analogs

Coelenterazine analogs 3a3e possessing various substituents at the para-position of the 6-phenyl group (R = CF3, F, H, OMe, and NMe 2) were synthesized, and the chemiluminescent properties of 3a3e in dimethyl sulfoxide (DMSO) were investigated quantitatively. Chemiluminescence maxima observed in the range of 454478nm showed a bathochromic shift as the electron-donating ability of R increased. Chemiluminescence quantum yields (φCL) were obtained in the range of 0.00060.0018. The analog 3a possessing the electron-withdrawing CF3 group showed a slight decrease in its φCL value. The fluorescence quantum yields (φF) of the light emitter, 2-acetamidopyrazine anions 4a --4e- , were observed in the range of 0.0050.21 and showed substituent dependency in that the increment in the electronwithdrawing ability of R decreases the φF value. The efficiency of generation of the singlet-excited 4a--4e- (φS) showed a small change in the range of 0.0080.015. From these quantitative analyses of the quantum efficiencies, we found that an electron-donating substituent R is not required for the efficient generation of a singlet-excited light emitter, but is required for the high φF of the emitter.