1998-63-6 Usage
Uses
Used in Pharmaceutical Research:
6-Chloro-2-(trifluoromethyl)-9H-purine is used as a research compound for investigating its pharmacological activities, such as antiviral and antitumor properties. Its unique structure allows for the exploration of its potential as a therapeutic agent against various diseases.
Used in Antiviral Applications:
In the field of antiviral research, 6-CHLORO-2-(TRIFLUOROMETHYL)-9H-PURINE is used as a potential antiviral agent. Its specific chemical structure may contribute to inhibiting viral replication or interfering with viral life cycles, offering a new avenue for the development of antiviral medications.
Used in Antitumor Applications:
6-Chloro-2-(trifluoromethyl)-9H-purine is also used as an antitumor agent in cancer research. Its potential to target and affect tumor cells makes it a candidate for further investigation into its role in cancer treatment, possibly leading to the development of novel anticancer drugs.
Used as a Building Block in Medicinal Chemistry:
In the pharmaceutical industry, 6-CHLORO-2-(TRIFLUOROMETHYL)-9H-PURINE is utilized as a synthetic intermediate for the preparation of various pharmaceuticals. Its unique functional groups and structural features make it a valuable component in the synthesis of new therapeutic agents with improved efficacy and selectivity.
Used in Agrochemical Development:
6-Chloro-2-(trifluoromethyl)-9H-purine is also used in the agrochemical industry as a building block for the development of new pesticides or plant growth regulators. Its chemical properties may offer novel modes of action or enhanced performance in agricultural applications.
Check Digit Verification of cas no
The CAS Registry Mumber 1998-63-6 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,9,9 and 8 respectively; the second part has 2 digits, 6 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 1998-63:
(6*1)+(5*9)+(4*9)+(3*8)+(2*6)+(1*3)=126
126 % 10 = 6
So 1998-63-6 is a valid CAS Registry Number.
InChI:InChI=1/C6H2ClF3N4/c7-3-2-4(12-1-11-2)14-5(13-3)6(8,9)10/h1-2H
1998-63-6Relevant academic research and scientific papers
PHOSPHODIESTERASE 4 INHIBITORS
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Page 73-74, (2008/06/13)
PDE4 inhibition is achieved by novel compounds of the Formula (I) wherein R1 and R2 are as defined herein.
PHOSPHODIESTERASE 4 INHIBITORS
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Page 43, (2008/06/13)
PDE4 inhibition is achieved by novel compounds of the Formula (I), wherein R1 and R2 are as defined herein.
Phosphodiesterase 4 inhibitors
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, (2008/06/13)
PDE4 inhibition is achieved by novel compounds of the Formula I: wherein R1 and R2 are as defined herein.
Synthesis and antirhinovirus activity of 6-(dimethylamino)-2-(trifluoromethyl)-9-(substituted benzyl)-9H-purines
Kelley,Linn,Selway
, p. 1757 - 1763 (2007/10/02)
A series of 6-(dimethylamino)-2-(trifluoromethyl)-9-(substituted benzyl)purines was synthesized and tested for antirhinovirus activity. Most of the compounds were synthesized by alkylation of 6-chloro-2-(trifluoromethyl)-9H-purine with the appropriate benzyl halide followed by displacement of the chloro group with dimethylamine. Alternatively, 6-(dimethylamino)-2-(trifluoromethyl)purine was alkylated with the appropriate benzyl halide. Although several different aryl substituents provided compounds with IC50's = 0.03 μM against rhinovirus serotype 1B, no congener was significantly more active than the parent 2. Twenty-three compounds were tested against 18 other serotypes, but none exhibited a uniform profile of activity.
