199863-40-6

Upstream product

• 5921-74-4 1-bromo-2-nonyne 
• 100-52-7 benzaldehyde 
• 32904-84-0 4-hydroxy-4-phenyl-2-butynyl methyl ether 
• 3761-92-0 n-hexylmagnesium bromide 

Downstream Products

• 774576-83-9 acetic acid 2-hexyl-1-phenyl-buta-2,3-dienyl ester 
• 1286282-59-4 2-hexyl-1-phenylbuta-2,3-dien-1-one 
• 774576-85-1 dimethyl 2-(1'-phenyl-2'-hexyl-2',3'-butadienyl)malonate 

Relevant academic research and scientific papers

Preparation of organoaluminum reagents from propargylic bromides and aluminum activated by PbCl2and their regio- And diastereoselective addition to carbonyl derivatives

Various propargylic and allenic aluminum reagents have been easily prepared by a direct insertion of aluminum into propargylic bromides in the presence of PbCl2 (1 mol%). These organoaluminum reagents react with carbonyl compounds to afford the

Studies on Cu(I)-catalyzed synthesis of simple 3-substituted 1,2-allenes and optically active 2-substituted secondary 2,3-allenols

The sequential treatment of terminal alkynes or propargylic alcohols with n-BuLi and MOMCl afforded the corresponding propargylic methyl ethers, which would react with primary alkyl Grignard reagents under the catalysis of CuBr to afford 3-substituted 1,2-allenes or 2-substituted secondary 2,3-allenols, respectively. The reaction may be applied to the synthesis of optically active 2-substituted secondary 2,3-allenols with up to >99% ee without any protection to the free hydroxyl group in the starting 4-hydroxy-2-alkynyl methyl ethers.

A new type of allyl- And prop-2-ynyl-manganese species: Generation and reactions with electrophiles

Tetrabutylmanganese ate complex 'Bu4MnLi2' reacts with allylic and prop-2-ynylic bromides to generate the corresponding allyl- and prop-2-ynyl-manganese species which further react with electrophiles such as aldehydes, ketones, epoxide and chlorosilanes to afford the corresponding allylated and prop-2-ynylated and/or allenylated products in high yields.