199872-29-2 Usage
Uses
Used in Medicinal Chemistry:
5-Quinolinecarboxylic acid, 8-methoxy-2-(trifluoromethyl)is used as a key intermediate in the synthesis of various pharmaceuticals for its unique structural features and potential biological activity.
Used in Pharmaceutical Development:
In the pharmaceutical industry, 5-Quinolinecarboxylic acid, 8-methoxy-2-(trifluoromethyl)is utilized as a building block for the development of new drugs, particularly those targeting specific diseases or conditions. Its unique structure allows for the design of molecules with enhanced potency, selectivity, and pharmacokinetic properties.
Used in Drug Synthesis:
5-Quinolinecarboxylic acid, 8-methoxy-2-(trifluoromethyl)serves as a valuable precursor in the synthesis of various drug candidates, enabling the creation of novel therapeutic agents with improved efficacy and safety profiles.
Used in Drug Design:
5-Quinolinecarboxylic acid, 8-methoxy-2-(trifluoromethyl)is employed in the design of innovative drug molecules, leveraging its unique structural elements to create new chemical entities with potential therapeutic benefits.
Used in Research and Development:
5-Quinolinecarboxylic acid, 8-methoxy-2-(trifluoromethyl)is utilized in research and development laboratories to explore its potential applications and optimize its use in the creation of new pharmaceuticals.
Check Digit Verification of cas no
The CAS Registry Mumber 199872-29-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,9,9,8,7 and 2 respectively; the second part has 2 digits, 2 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 199872-29:
(8*1)+(7*9)+(6*9)+(5*8)+(4*7)+(3*2)+(2*2)+(1*9)=212
212 % 10 = 2
So 199872-29-2 is a valid CAS Registry Number.
199872-29-2Relevant academic research and scientific papers
SYNTHESIS OF QUINOLINE 5-CARBOXAMIDES USEFUL FOR THE PREPARATION OF PDE IV INHIBITORS
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Page/Page column 22, (2010/02/11)
In one embodiment, the present application discloses a process for making the compound of the formula:
8-Methoxyquinolines as PDE4 inhibitors.
Billah, Motasim,Buckley, George M,Cooper, Nicola,Dyke, Hazel J,Egan, Robert,Ganguly, Ashit,Gowers, Lewis,Haughan, Alan F,Kendall, Hannah J,Lowe, Christopher,Minnicozzi, Michael,Montana, John G,Oxford, Janet,Peake, Joanna C,Picken, C Louise,Piwinski, John J,Naylor, Robert,Sabin, Verity,Shih, Neng-Yang,Warneck, Julie B H
, p. 1617 - 1619 (2007/10/03)
The synthesis and pharmacological profile of a novel series of 2-substituted 8-methoxyquinolines is described. The 2-trifluoromethyl compound was found to be a potent inhibitor of phosphodiesterase type 4 (PDE4).
