199874-57-2Relevant academic research and scientific papers
New Syntheses of Benzobarrelenes
Pu, Lin,Grubbs, Robert H.
, p. 1351 - 1353 (1994)
New syntheses of both substituted and unsubstituted benzobarrelenes are described.Treatment of 3,5-cyclohexadiene-cis-1,2-diol with benzaldehyde dimethyl acetal in the presence of a catalytic amount of p-toluenesulfonic acid gave 1,2-(benzylidenedioxy)-3,5-cyclohexadiene (2).Addition of benzynes to 2 provided 3 and 4.Treatment of 3 and 4 with excess LDA and potassium tert-butoxide afforded benzobarrelenes 1 and 5 in good yields.
