Journal of Organic Chemistry p. 1351 - 1353 (1994)
Update date:2022-08-03
Topics:
Pu, Lin
Grubbs, Robert H.
New syntheses of both substituted and unsubstituted benzobarrelenes are described.Treatment of 3,5-cyclohexadiene-cis-1,2-diol with benzaldehyde dimethyl acetal in the presence of a catalytic amount of p-toluenesulfonic acid gave 1,2-(benzylidenedioxy)-3,5-cyclohexadiene (2).Addition of benzynes to 2 provided 3 and 4.Treatment of 3 and 4 with excess LDA and potassium tert-butoxide afforded benzobarrelenes 1 and 5 in good yields.
View MoreShanghai birch chemical technology co.,ltd
Contact:+86-21-54096810
Address:No.2588,Jungong Road,Shanghai,China
Contact:86-512-87182055
Address:No.128 Fangzhou Rd, Suzhou Industrial Park, China, 215125, China
Jinan Yufeng Bioengineering Co., Ltd.
Contact:+86-531-83130545/83130528/83130525/83130505
Address:Rm415,Building2,No19,Huaneng Road,Jinan, Shandong, China
Chengdu Green Young Biopharmaceutical INC
Contact:+86-28-85337952
Address:1-B-26,Tianhe Industry Park, No.1480 of Tianfu Road,Chengdu,P.R.China,610000
Shanghai Xinda Pharmaceuticals Co., Ltd.
Contact:86-21-33692333-8008
Address:999 Linxian Road, Jinshan Industrial Park, Shanghai, China
Doi:10.1039/jr9650003616
(1965)Doi:10.1021/ja01544a033
(1958)Doi:10.1248/cpb.44.793
(1996)Doi:10.1016/S0040-4020(97)10199-5
(1997)Doi:10.1016/S0040-4039(97)10079-X
(1997)Doi:10.1039/a704203e
(1997)