19993-97-6

Basic information

• Product Name: 3-(4-methoxyphenyl)[1,2,4]triazolo[3,4-b][1,3]benzothiazole
• Synonyms: 3-(4-methoxyphenyl)[1,2,4]triazolo[3,4-b][1,3]benzothiazole
• CAS NO: 19993-97-6
• Molecular Weight: 281.338
• Mol File: 19993-97-6.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: 3-(4-methoxyphenyl)[1,2,4]triazolo[3,4-b][1,3]benzothiazole(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(4-methoxyphenyl)[1,2,4]triazolo[3,4-b][1,3]benzothiazole(19993-97-6)
• EPA Substance Registry System: 3-(4-methoxyphenyl)[1,2,4]triazolo[3,4-b][1,3]benzothiazole(19993-97-6)

Safety Data

• Hazardous Substances Data: 19993-97-6(Hazardous Substances Data)

Upstream product

• 615-36-1 2-bromoaniline 
• 13037-60-0 1-bromo-2-isothiocyanatobenzene 
• 123-11-5 4-methoxy-benzaldehyde 
• 615-21-4 1,3-benzothiazol-2-ylhydrazine 
• 149-30-4 2-Mercaptobenzothiazole 
• 193738-04-4 4-(2-Chloro-phenyl)-5-(4-methoxy-phenyl)-2,4-dihydro-[1,2,4]triazole-3-thione 
• 5347-22-8 2-[2-(4-methoxybenzylidene)hydrazino]-1,3-benzothiazole 
• 615-20-3 2-chlorobenzo[d][1,3]thiazole 
• 3290-99-1 4-methoxybenzoic acid hydrazide 
• 2740-81-0 2-chlorophenylisothiocyanate 

Relevant articles and documents

Convenient synthesis of benzo[4,5]thiazolo[2,3-c][1,2,4]triazoles with 1 mol% CuCl2·2H2O as catalyst in water

A convenient and efficient procedure for the synthesis of benzo[4,5]thiazolo [2,3-c][1,2,4]triazoles has been developed via a tandem intermolecular C-N bond and intramolecular C-S bond formation sequence from o-bromo-arylisothiocyanates and aroylhydrazides. A series of benzo[4,5]thiazolo[2,3-c][1,2,4]triazoles were provided in excellent overall yields with 1 mol% CuCl2·2H2O/1 mol% 1,10-phenanthroline as the catalyst and water as the solvent. This journal is

Synthesis of new triazolo and pyrazolo benzothiazoles

Benzothiazole-2-thiol 1 on heating with excess of hydrazine hydrate yields 2-hydrazino-1,3-benzothiazole (2). Compound 2 on reaction with carbon disulfide in alkaline medium affords [1,2,4] triazolo [3,4-b] [1,3] benzothiazole-3-thiol (3). Condensation of 2 with various substituted aryl aldehydes yields corresponding hydrazine derivatives (4), which on cyclisation with acetic anhydride gave corresponding [1,2,4] triazolo [3,4-6] [1,3] benzothiazoles (5). Some other triazolo derivatives (6,7,8) of benzothiazole were obtained by the cyclization of 2 with benzoyl chloride, acetyl chloride and formic acid respectively. Again compound 2 on condensation with acetyl acetone and ethylacetoacetate gives pyrazolo derivatives (9,10) respectively. The synthesized compounds were characterized by elemental and spectral analysis.

Thallium(III) salts mediated oxidative cyclization of arenecarbaldehyde benzothiazol-2-ylhydrazones to bridged head nitrogen heterocycles

Oxidation of arenecarbaldehydebenzothiazol-2-ylhydrazones (4) with thallium (III) acetate in refluxing acetic acid, thallium (III) acetate and thallium (III) nitrate in acetonitrile in presence of p-toluene sulphonic acid afforded 3-aryl-1,2,4-triazolo [3