5347-22-8Relevant academic research and scientific papers
Arylhydrazones Derivatives Containing a Benzothiazole Moiety, Efficient Ligands in the Palladium-Catalyzed Mizoroki–Heck and Suzuki–Miyaura Cross-coupling Reactions under IR Irradiation
Ortega-Jiménez, Fernando,Penieres-Carrillo, José Guillermo,López-Cortés, José Guadalupe,Carmen Ortega-Alfaro,Lagunas-Rivera, Selene
, p. 1881 - 1888 (2017/09/12)
A simple arylhydrazone containing the benzothiazole moiety which may be used as an efficient ligand in the palladium-catalyzed Mizoroki–Heck and Suzuki–Miyaura cross-coupling reactions, under infrared irradiation as an alternative source of energy, is presented. The reactions proceeded with extremely high efficiency under mild conditions and produced very good yields.
Antimalarial activity of small-molecule benzothiazole hydrazones
Sarkar, Souvik,Siddiqui, Asim A.,Saha, Shubhra J.,De, Rudranil,Mazumder, Somnath,Banerjee, Chinmoy,Iqbal, Mohd S.,Nag, Shiladitya,Adhikari, Susanta,Bandyopadhyay, Uday
, p. 4217 - 4228 (2016/07/11)
We synthesized a new series of conjugated hydrazones that were found to be active against malaria parasite in vitro, as well as in vivo in a murine model. These hydrazones concentration-dependently chelated free iron and offered antimalarial activity. Upo
Study of oxidative cyclization using PhI(OAc)2 in the formation of benzo[4,5]thiazolo[2,3- C ][1,2,4]triazoles and related heterocycles - Scope and limitations
Demmer, Charles S.,Jorgensen, Morten,Kehler, Jan,Bunch, Lennart
, p. 1279 - 1282 (2014/06/10)
A one-pot, two-step reaction for the synthesis of benzo[4,5]thiazolo[2,3-c] [1,2,4]triazoles and related heterocycles under mild conditions was herein developed. The key step of this transformation is an oxidative cyclization employing PhI(OAc)2/sub
Synthesis of new triazolo and pyrazolo benzothiazoles
Deshmukh,Patil,Jadhav,Shejwal
, p. 163 - 166 (2013/09/23)
Benzothiazole-2-thiol 1 on heating with excess of hydrazine hydrate yields 2-hydrazino-1,3-benzothiazole (2). Compound 2 on reaction with carbon disulfide in alkaline medium affords [1,2,4] triazolo [3,4-b] [1,3] benzothiazole-3-thiol (3). Condensation of 2 with various substituted aryl aldehydes yields corresponding hydrazine derivatives (4), which on cyclisation with acetic anhydride gave corresponding [1,2,4] triazolo [3,4-6] [1,3] benzothiazoles (5). Some other triazolo derivatives (6,7,8) of benzothiazole were obtained by the cyclization of 2 with benzoyl chloride, acetyl chloride and formic acid respectively. Again compound 2 on condensation with acetyl acetone and ethylacetoacetate gives pyrazolo derivatives (9,10) respectively. The synthesized compounds were characterized by elemental and spectral analysis.
STRUCTURE OF 2-BENZOTHIAZOLYLHYDRAZONES OF AROMATIC AND ALIPHATIC ALDEHYDES
Shmelev, L. V.,Ol'khovikova, N. B.,Pervova, I. G.,Lipunova, G. N.,Orlova, E. E.,Lipunov, I. N.
, p. 472 - 479 (2007/10/02)
On the basis of data of 13C and 1H NMR and IR spectroscopy, it was shown that 2-benzothiazolylhydrazones of aliphatic aldehydes were in solution as a mixture of E and Z isomers, and hydrazones of aromatic aldehydes were in solution only as E isomers.All i
Preparation and Spectroscopic Properties of 2-Benzothiazolyl Araldehyde Hydrazones
Hearn, Michael J.,Schulz, Jeannette,Sinha, Anvita,Collins, Pamela,Hallenbeck, Susan,Kustin, Michael
, p. 521 - 524 (2007/10/02)
Notwithstanding its tendency toward air oxidation in solution, 2-hydrazinobenzothiazole I reacted with aromatic aldehydes in ethanol to give the corresponding hydrazones III-XV in high yields and analytical purity.In related examples, acylation took place
SYNTHESIS AND TRANSFORMATIONS OF S- AND N-SUBSTITUTED 2-MERCAPTOBENZOTHIAZOLES
Rutavichyus, A. I.,Iokubaitite, S. P.
, p. 33 - 36 (2007/10/02)
2-Mercaptobenzothiazole reacts with alkyl halides and hydrazine hydrate in the thiol form, and with formaldehyde in the thione form.The alkylation of 2-mercaptobenzothiazolidin-3-yl-methanol has been performed with sulfoalkyl halides and with propan-1,3-s
