20001-64-3

Basic information

• Product Name: 1-CHLORO-2-(1-CHLOROETHYL)BENZENE
• Synonyms: 1-(2-Chlorophenyl)ethyl chloride; Benzene, 1-chloro-2-(1-chloroethyl)-
• CAS NO: 20001-64-3
• Molecular Formula: C₈H₈Cl₂
• Molecular Weight: 175.06
• Mol File: 20001-64-3.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 215.5°C at 760 mmHg
• Flash Point: 80.8°C
• Appearance: /
• Density: 1.196g/cm³
• Vapor Pressure: 0.216mmHg at 25°C
• Refractive Index: 1.534
• CAS DataBase Reference: 1-CHLORO-2-(1-CHLOROETHYL)BENZENE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-CHLORO-2-(1-CHLOROETHYL)BENZENE(20001-64-3)
• EPA Substance Registry System: 1-CHLORO-2-(1-CHLOROETHYL)BENZENE(20001-64-3)

Safety Data

• Hazardous Substances Data: 20001-64-3(Hazardous Substances Data)

Usage

General Description

1-CHLORO-2-(1-CHLOROETHYL)BENZENE is a chemical compound with the molecular formula C8H8Cl2. It is a colorless to light yellow liquid with a strong, sweet odor, and it is often used as an intermediate in the production of pesticides and pharmaceuticals. This chemical is considered to be hazardous if inhaled, ingested, or if it comes into contact with the skin or eyes. Exposure to 1-CHLORO-2-(1-CHLOROETHYL)BENZENE can cause irritation, respiratory issues, and central nervous system effects. It is important to handle this chemical with caution and to follow proper safety protocols when working with it.

InChI:InChI=1/C8H8Cl2/c1-6(9)7-4-2-3-5-8(7)10/h2-6H,1H3

Upstream product

• 13524-04-4 2'-chloro-sec-phenethyl alcohol 
• 2142-68-9 1-(2-chlorophenyl)ethanone 
• 89-96-3 1-chloro-2-ethylbenzene 

Downstream Products

• 66897-87-8 N-Allyl-N-[1-(2-chloro-phenyl)-ethyl]-benzenesulfonamide 

Relevant articles and documents

Iron-catalysed enantioconvergent Suzuki-Miyaura cross-coupling to afford enantioenriched 1,1-diarylalkanes

The first stereoconvergent Suzuki-Miyaura cross-coupling reaction was developed to afford enantioenriched 1,1-diarylalkanes. An iron-based complex containing a chiral cyanobis(oxazoline) ligand framework was best to obtain enantioenriched 1,1-diarylalkanes from cross-coupling reactions between unactivated aryl boronic esters and benzylic chlorides. Enhanced yields were obtained when 1,3,5-trimethoxybenzene was used as an additive, which is hypothesized to extend the lifetime of the iron-based catalyst. Exceptional enantioselectivities were obtained with challenging ortho-substituted benzylic chlorides. This journal is

Ketone-catalyzed photochemical C(sp3)–H chlorination

Photoexcited arylketones catalyze the direct chlorination of C(sp3)–H groups by N- chlorosuccinimide. Acetophenone is the most effective catalyst for functionalization of unactivated C–H groups while benzophenone provides better yields for benzylic C–H functionalization. Activation of both acetophenone and benzophenone can be achieved by irradiation with a household compact fluorescent lamp. This light-dependent reaction provides a better control of the reaction as compared to the traditional chlorination methods that proceed through a free radical chain propagation mechanism.

NOVEL 5-SUBSTITUTED 7-AMINO-[1,3]THIAZOLO[4,5-D]PYRIMIDINE DERIVATIVES

There are disclosed novel 5-substituted 7-amino-[1,3]thiazolo[4,5-d]pyrimidine derivatives of formula (I) wherein R1, R2, R3, R4 and R5 are as defined in the specification, and pharmaceutically accept