2002-94-0 Usage
Uses
Used in Pharmaceutical and Agrochemical Industries:
3-(PENTAFLUOROPHENYL)PROPIONIC ACID serves as a crucial building block in the synthesis of pharmaceuticals and agrochemicals. Its unique structure and reactivity make it an essential component in the development of new drugs and pesticides.
Used in Specialty Materials Production:
3-(PENTAFLUOROPHENYL)PROPIONIC ACID is utilized in the production of specialty materials, where its properties contribute to the creation of high-performance materials with specific characteristics, such as enhanced stability or improved performance in certain conditions.
Used as a Chemical Intermediate:
3-(PENTAFLUOROPHENYL)PROPIONIC ACID also functions as a chemical intermediate in various chemical reactions, enabling the synthesis of more complex molecules and compounds for diverse applications.
Used in the Study of the Endocannabinoid System:
As a potent inhibitor of fatty acid amide hydrolase, an enzyme involved in the endocannabinoid system, 3-(PENTAFLUOROPHENYL)PROPIONIC ACID is a valuable tool for researchers studying this biological pathway. Its ability to modulate enzyme activity provides insights into the system's role in various physiological processes.
Used in the Flavor and Fragrance Industry:
3-(PENTAFLUOROPHENYL)PROPIONIC ACID has potential applications in the flavor and fragrance industry, where its unique properties can be harnessed to create novel scents or enhance existing ones. Its versatility in this field contributes to the development of innovative products with distinct olfactory profiles.
Check Digit Verification of cas no
The CAS Registry Mumber 2002-94-0 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 2,0,0 and 2 respectively; the second part has 2 digits, 9 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 2002-94:
(6*2)+(5*0)+(4*0)+(3*2)+(2*9)+(1*4)=40
40 % 10 = 0
So 2002-94-0 is a valid CAS Registry Number.
InChI:InChI=1/C9H5F5O2/c10-5-3(1-2-4(15)16)6(11)8(13)9(14)7(5)12/h1-2H2,(H,15,16)
2002-94-0Relevant academic research and scientific papers
Synthesis of trifluoromethyl ketones by palladium-catalyzed cross-coupling reaction of phenyl trifluoroacetate with organoboron compounds
Kakino,Shimizu,Yamamoto
, p. 371 - 376 (2007/10/03)
Cross-coupling reaction of aryl trifluoroacetates with organoboron compounds catalyzed by palladium complexes gives trifluoromethyl ketones in moderate to excellent yields under mild conditions. The catalytic process has been designed on the basis of fundamental studies dealing with oxidative addition of phenyl trifluoroacetate to a Pd(0) complex to give a (phenoxo)(trifluoroacetyl)palladium(II) complex and its subsequent reaction with phenylboronic acid to liberate phenyl trifluoromethyl ketone. The catalytic cycle is proposed to be composed of (a) oxidative addition of the ester to give acyl(aryloxo)palladium intermediate, (b) the subsequent transmetallation with arylboron compounds, and (c) reductive elimination. Palladium(0) complexes, as well as catalysts prepared in situ from palladium acetate and 3 molar amounts of tributylphosphine or phosphite at room temperature, serve as convenient and effective catalysts. The process is applicable to a wide range of phenyl- and naphthylboronic acids to give various aryl trifluoromethyl ketones under mild conditions. Aryl perfluoroalkyl ketone derivatives can be similarly prepared in high yields from various phenyl perfluoroalkanecarboxylates and arylboronic acids.
