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6-DifluoroMethoxyindole is a fluorinated indole derivative with the molecular formula C9H6F2NO. It belongs to the class of organic compounds known as methoxyindoles and is characterized by its aromatic nature, a methoxy group, and two fluorine atoms attached to the indole ring. This chemical compound can be synthesized through various methods and is of interest to the scientific and medical community due to its potential applications in pharmaceutical and research fields.

200207-21-2

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200207-21-2 Usage

Uses

Used in Pharmaceutical Industry:
6-DifluoroMethoxyindole is used as a chemical intermediate for the development of new drug compounds and pharmaceutical products. Its unique structure and properties make it a promising candidate for the synthesis of novel therapeutic agents.
Used in Research Applications:
6-DifluoroMethoxyindole is utilized as a research tool in the scientific community to study its specific properties and potential uses. Ongoing research may reveal further applications for 6-DifluoroMethoxyindole, expanding its utility in various fields.

Check Digit Verification of cas no

The CAS Registry Mumber 200207-21-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,0,0,2,0 and 7 respectively; the second part has 2 digits, 2 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 200207-21:
(8*2)+(7*0)+(6*0)+(5*2)+(4*0)+(3*7)+(2*2)+(1*1)=52
52 % 10 = 2
So 200207-21-2 is a valid CAS Registry Number.

200207-21-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name 6-(Difluoromethoxy)-1H-indole

1.2 Other means of identification

Product number -
Other names 6-difluoromethoxyindole

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:200207-21-2 SDS

200207-21-2Relevant articles and documents

PYRIDINYL AND PYRAZINYL-(AZA)INDOLSULFONAMIDES

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Page/Page column 86-87; 89, (2020/01/11)

The present invention relates to pyridinyl and pyrazinyl-(aza)indolsulfonamides having GPR17 modulator activity. The compounds have utility in the treatment of a variety of GPR17-associated disorders.

QUINUCLIDINES FOR MODULATING ALPHA 7 ACTIVITY

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Paragraph 0350, (2016/02/29)

Provided are substituted quinuclidine compounds, pharmaceutical compositions comprising such compounds, and methods of modulating α7 nicotinic acetylcholine receptors and treating neurological disorders using such compounds.

Discovery of N-(4′-(indol-2-yl)phenyl)sulfonamides as novel inhibitors of HCV replication

Chen, Guangming,Ren, Hongyu,Turpoff, Anthony,Arefolov, Alexander,Wilde, Richard,Takasugi, James,Khan, Atiyya,Almstead, Neil,Gu, Zhengxian,Komatsu, Takashi,Freund, Connie,Breslin, Jamie,Colacino, Joseph,Hedrick, Jean,Weetall, Marla,Karp, Gary M.

, p. 3942 - 3946 (2013/07/27)

A series of novel 2-phenylindole analogs were synthesized and evaluated for activity in subgenomic HCV replicon inhibition assays. Several compounds containing small alkyl sulfonamides on the phenyl ring exhibiting submicromolar EC50 values against the genotype 1b replicon were identified. Among these, compound 25d potently inhibited the 1b replicon (EC50 = 0.17 μM) with 147-fold selectivity with respect to cytotoxicity. Compound 25d was stable in the presence of human liver microsomes and had a good pharmacokinetic profile in rats with an IV half-life of 4.3 h and oral bioavailability (F) of 58%.

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