20024-90-2Relevant academic research and scientific papers
Enantio- and regioselective intermolecular benzylic and allylic C-H bond amination
Nishioka, Yota,Uchida, Tatsuya,Katsuki, Tsutomu
supporting information, p. 1739 - 1742 (2013/04/23)
Smooth salen: Ru(CO)-salen complex 1 is an effective catalyst for asymmetric benzylic and allylic C-H bond amination using 2-(trimethylsilyl) ethanesulfonyl azide (SESN3) as the nitrene source. The reaction proceeded with high enantioselectivity and excellent regioselectivity. An ethyl group can be selectively aminated, even in the presence of an n-propyl group. No migration or isomerization of the double bond was observed. Copyright
Arenes Disubstituted with Primary Alkyl Groups from Xylylene Dianions
Bates, Robert B.,Ogle, Craig A.
, p. 3949 - 3952 (2007/10/02)
Xylenes were converted into dianions 1.Reaction of dianions 1 with dialkyl sulfates gave symmetrical dialkylbenzenes 2 (R = R'), while methyl iodide caused oxidative coupling followed by alkylation to give 8.Unsymmetrical dialkylbenzenes 2 (R =/= R') were made by an indirect route involving monoanions 9 and 11.Reactions of dianions 1 with dihalides gave cyclophanes o-3 (n = 5,6,9), m-3 (n = 8-10), and p-3 (n = 9-11) and cyclophanes o-4 (n = 2,5,7,9) and m-4 (n = 2,6,7).Dianion 5 from 2,6-lutidine was used to prepare nitrogen analogues of 2 (R = R') and m-3 (n = 8-10).
