200283-08-5

Basic information

• Product Name: Carbamic acid, [2-[[(1,1-dimethylethoxy)carbonyl]amino]ethyl](2-hydroxyethyl)-, 1,1-dimethylethyl ester
• CAS NO: 200283-08-5
• Molecular Formula: C14H28N2O5
• Molecular Weight: 304.387
• Mol File: 200283-08-5.mol
• Article Data: 8

Chemical Properties

• CAS DataBase Reference: Carbamic acid, [2-[[(1,1-dimethylethoxy)carbonyl]amino]ethyl](2-hydroxyethyl)-, 1,1-dimethylethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Carbamic acid, [2-[[(1,1-dimethylethoxy)carbonyl]amino]ethyl](2-hydroxyethyl)-, 1,1-dimethylethyl ester(200283-08-5)
• EPA Substance Registry System: Carbamic acid, [2-[[(1,1-dimethylethoxy)carbonyl]amino]ethyl](2-hydroxyethyl)-, 1,1-dimethylethyl ester(200283-08-5)

Safety Data

• Hazardous Substances Data: 200283-08-5(Hazardous Substances Data)

Upstream product

• 24424-99-5 di-tert-butyl dicarbonate 
• 111-41-1 2-(2-Aminoethylamino)ethanol 
• 208577-84-8 [2-(2-Hydroxy-ethylamino)-ethyl]-carbamic acid tert-butyl ester 

Downstream Products

• 200283-09-6 N-(O-(3-maleinimidobenzoyl)-2-hydroxyethyl)-N,N'-bis-tertiarybutyloxycarbonyl-1,2-diaminoethane 
• 554-68-7 triethylamine hydrochloride 
• 120131-72-8 N-(2-aminoethyl)-N-[2-[[(1,1-dimethylethoxy)carbonyl]amino]ethyl]carbamate-1,1-dimethylethyl ester 

Relevant articles and documents

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A convenient approach to the construction of a galacturonic acid based macrocycle containing an amide group and a triazole ring has been achieved. The key step relies on the efficient formation of a 16-membered ring by a copper-catalysed intramolecular cycloaddition reaction applied to analkyne-azide galacturonate. Depending on the reaction conditions, the outcome of the 1,3-dipolar cycloaddition varied; the expected intramolecular 1,4-triazole was obtained as well as a C2-symmetric dimer in different ratios. A preliminary study of the complexation properties of this macrocycle towards CuII cations revealed the formation of cryptates in a 1:1 metal/ligand ratio. A galacturonic acid based macrocycle containing an amide group and a triazole ring has been synthesized by a procedure involving a copper-catalysed intramolecular cycloaddition reaction as the key step. The results of a preliminary study of the complexation properties of this macrocycle towards CuII cations are described. Copyright

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