200345-50-2Relevant academic research and scientific papers
Highly regioselective ring opening of epoxides using NaN3: A short and efficient synthesis of (-)-cytoxazone
Boruwa, Joshodeep,Borah, Jagat C.,Kalita, Biswajit,Barua, Nabin C.
, p. 7355 - 7358 (2007/10/03)
A convenient and efficient synthesis of 1,2-azido alcohols has been achieved by regioselective ring opening of epoxides using NaN3 and 4 ? molecular sieves in acetonitrile. The utility of this method has been demonstrated by achieving a short synthesis of (-)-cytoxazone in 48% overall yield.
Synthetic utility of tert-butyl azidoacetate on the Hemetsberger-Knittel reaction (synthetic studies of indoles and related compounds part 47)
Kondo, Kazuhiro,Morohoshi, Sachiko,Mitsuhashi, Masaharu,Murakami, Yasuoki
, p. 1227 - 1231 (2007/10/03)
The synthetic utility of tert-butyl azidoacetate (7) on the Hemetsberger-Knittel reaction is described. The following two findings are disclosed by using tert-butyl azidoacetate (7): i) in the first step for the synthesis of ethyl indole-2-carboxylate 4,
New findings on the hemetsberger-knittel reaction (synthetic studies on indoles and related compounds. XLIII(1))
Murakami, Yasuoki,Watanabe, Toshiko,Suzuki, Hideharu,Kotake, Nobuyo,Takahashi, Tomoko,Toyonari, Kiyono,Ohno, Masami,Takase, Kyoko,Suzuki, Takayuki,Kondo, Kazuhiro
, p. 1739 - 1744 (2007/10/03)
In the Hemetsberger-Knittel reaction for indole synthesis, the intermediate ethyl 2-azido-3-hydroxy-3-aryl-propionate (4) was found to be formed in the reaction of arylaldehyde 1 with ethyl azidoacetate at a lower temperature (-30°C) as the main product,
