200405-33-0

Upstream product

• 2628-16-2 p-acetoxystyrene 
• 621-84-1 O-benzyl carbamate 

Downstream Products

• 851714-36-8 [2-(4-hydroxy-phenyl)-2-(S)-methoxy-ethyl]carbamic acid benzyl ester 
• 640234-75-9 (S)-4-(2-amino-1-methoxy-ethyl)phenol 
• 826-01-7 (S)-1-hydroxy-1-(4-hydroxyphenyl)-2-aminoethane 
• 640234-74-8 acetic acid 4-(2-benzyloxycarbonylamino-1-(S)-methoxy-ethyl)phenyl ester 

Relevant academic research and scientific papers

COMPOUNDS AND METHODS FOR TREATMENT OF CANCER AND MODULATION OF PROGRAMMED CELL DEATH FOR MELANOMA AND OTHER CANCER CELLS

Compounds and related methods for synthesis, and the use of compounds and combination therapies for the treatment of cancer and modulation of apoptosis in cells are disclosed. The generation of synthetic combinatorial libraries and the evaluation of library member compounds regarding induction of apoptosis selectively in cancer cells are disclosed. Compounds, methods of making the compounds, and therapeutic methods with application against breast cancer cells, melanoma cancer cells, colon cancer cells, and other cancer cells are described.

The use of pH to influence regio- and chemoselectivity in the asymmetric aminohydroxylation of styrenes

(Matrix presented) The pH-controlled Sharpless asymmetric aminohydroxylation (AA) of styrenes provides 1-aryl-2-amino ethanols (regioisomer E enantio-, chemo-, and regioselectivity. As existing AA protocols typically give regioisomer A as the major reaction product when usin nitrogen sources, this method is a convenient alternative for the selective production of regioisomer B.