200411-13-8

Upstream product

• 3400-31-5 2-chloro-N-methylbenzamide 
• 108-98-5 thiophenol 
• 29879-69-4 3-hydroxy-2-methyl-isoindolin-1-one 
• 550-44-7 N-methylphthalimide 
• 408325-03-1 2-methyl-3-phenylsulfanyl-2,3-dihydro-isoindol-1-one 
• 200411-11-6 N-(2-chlorobenzoyl)-N-methylaminomethyl phenyl sulfone 

Relevant academic research and scientific papers

SmI2-promoted tandem desulfurization and reductive coupling reactions of aromatic lactams with carbonyl compounds

Treatment of sulfur-substituted aromatic lactams with carbonyl compounds in the presence of samarium(II) diiodide was found to undergo novel tandem desulfurization and reductive coupling reactions to generate α-hydroxyalkylated lactams in high yield. Ster

A short and efficient synthesis of 3-diphenylphosphoryl- and 3-diethoxyphosphoryl(aza)isoindolinones: Extension to the sulfonylated analogs

A variety of 3-diphenylphosphoryl- and 3-diethoxyphosphoryl(aza)isoindolinones have been efficiently prepared by aryne- and hetaryne-mediated cyclization of phosphorylated α-amino carbanions derived from suitably substituted 2- and 3-halobenzamide and 3-chloropyridine-4-carboxamide derivatives. The synthesis of some 3-sulfonylated analogs by extension of this principle has been achieved.