200435-88-7Relevant academic research and scientific papers
Synthesis of 2'-O,4'-C-methyleneuridine and -cytidine. Novel bicyclic nucleosides having a fixed c3-endo sugar puckering
Obika, Satoshi,Nanbu, Daishu,Hari, Yoshiyuki,Morio, Ken-Ichiro,In, Yasuko,Ishida, Toshimasa,Imanishi, Takeshi
, p. 8735 - 8738 (1997)
2'-O,4'-C-Methyleneuridine and -cytidine, novel bicyclic nucleoside analogs having a typical C3'-endo sugar puckering, were synthesized starting from uridine via a several-step sequence.
Bicyclonucleoside and oligonucleotide analogue
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, (2008/06/13)
An oligo- or polynucleotide analogue having one or more structures of the general formula where B is a pyrimidine or purine nucleic acid base, or an analogue thereof, is disclosed. The use of this analogue provides an oligonucleotide analogue antisense molecule, which is minimally hydrolyzable with an enzyme in vivo, has a high sense strand binding ability, and is easily synthesized.
Novel bicyclonucleoside and oligonucleotide analogue
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, (2008/06/13)
An oligo- or polynucleotide analogue having one or more structures of the general formula where B is a pyrimidine or purine nucleic acid base, or an analogue thereof, is disclosed. The use of this analogue provides an oligonucleotide analogue antisense molecule, which is minimally hydrolyzable with an enzyme in vivo, has a high sense strand binding ability, and is easily synthesized.
Bicyclonucleoside and oligonucleotide analogues
-
, (2008/06/13)
An oligo- or polynucleotide analogue having one or more structures of the general formula where B is a pyrimidine or purine nucleic acid base, or an analogue thereof, is disclosed. The use of this analogue provides an oligonucleotide analogue antisense molecule, which is minimally hydrolyzable with an enzyme in vivo, has a high sense strand binding ability, and is easily synthesized.
