Synthesis of 2'-O,4'-C-methyleneuridine and -cytidine. Novel bicyclic nucleosides having a fixed c3-endo sugar puckering

DOI: 10.1016/S0040-4039(97)10322-7

Source and publish data:

Tetrahedron Letters p. 8735 - 8738 (1997)

Update date:2022-08-04

Topics:

Authors:

Obika, Satoshi

Nanbu, Daishu

Hari, Yoshiyuki

Morio, Ken-Ichiro

In, Yasuko

Ishida, Toshimasa

Imanishi, Takeshi

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Article abstract of DOI:10.1016/S0040-4039(97)10322-7

2'-O,4'-C-Methyleneuridine and -cytidine, novel bicyclic nucleoside analogs having a typical C₃'-endo sugar puckering, were synthesized starting from uridine via a several-step sequence.

Full text of DOI:10.1016/S0040-4039(97)10322-7

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Product name:2',3'-O-benzylidene-4'-(p-toluenesulfonyloxymethyl)uridine

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