200636-33-5

Upstream product

• 200636-28-8 2,2-Dimethyl-propionic acid 3-[(S)-1-((R)-2,2-dimethyl-[1,3]dioxolan-4-yl)-2-hydroxy-but-3-enyloxy]-propyl ester 
• 337970-23-7 (2R,3S,4RS)-1,2-O-isopropylidene-4-pivaloyloxy-3-(3-pivaloyloxypropoxy)-5-hexene-1,2-diol 
• 337970-24-8 (2R,3S,4RS)-4-pivaloyloxy-3-(3-pivaloyloxypropoxy)-5-hexene-1,2-diol 
• 3282-30-2 pivaloyl chloride 
• 4039-83-2 3-(4-methoxybenzyloxy)propyne 
• 200636-30-2 (2R,3S,4RS)-1,2-epoxy-4-pivaloyloxy-3-(3-pivaloyloxypropoxy)-5-hexene 

Downstream Products

• 200636-42-6 (Z)-2-[(3R,4R,5R)-3,5-bis(tert-butyldimethylsilyloxy)-4-(3-tert-butyldimethylsilyloxypropoxy)-2-methylenecyclohexylidene]ethanol 
• 200636-54-0 [3R-(1Z,3β,4α,5α)]-[2-[3,5-bis[(1,1-dimethylethyl)dimethylsilyloxy]-4-[3-[(1,1-dimethylethyl)dimethylsilyloxy]propoxy]-2-methylenecyclohexylidene]ethyl]diphenylphosphine oxide 
• 200636-50-6 [3R-(1Z,3β,4α,5α)]-2-[3,5-bis[(1,1-dimethylethyl)dimethylsilyloxy]-4-[3-[(1,1-dimethylethyl)dimethylsilyloxy]propoxy]-2-methylenecyclohexylidene]-1-chloroethane 
• 104121-92-8 Eldecalcitol 
• 933779-88-5 (3RS,4R,5R)-4-(3-hydroxypropoxy)-9-(p-methoxyphenylmethoxy)non-1-en-7-yne-3,5-diol 

Relevant academic research and scientific papers

Convergent synthesis of 1α,25-dihydroxy-2β-(3-hydroxypropoxy)vitamin D3 (ED-71)

A convergent and versatile synthesis of the potent vitamin D analog, 1α,25-dihydroxy-2β-(3-hydroxypropoxy)vitamin D3 [1] (ED-71) is described.

Two convergent approaches to the synthesis of 1,25-dihydroxy 2-(3-hydroxypropoxy)vitamin D3 (ED-71) by the lythgoe and thf trost coupling reactions

Two convergent syntheses of 1,25-dihydroxy-2-(3-hydroxypropoxy)vitamin D3 (ED-71) by the Lythgoe coupling reaction between the A-ring phosphine oxide and the C/D-ring ketone and the Trost coupling reaction between the A-ring ene-yne and the C/D-ring bromomethylene are described.