20067-15-6

Usage

Uses

Used in Pharmaceutical Industry:
5-Iodo-3-Methyl-isothiazole is used as a synthetic intermediate for the development of new drugs and medical treatments, leveraging its antimicrobial properties to contribute to the efficacy of various pharmaceutical formulations.
Used in Agrochemical Industry:
In the agrochemical sector, 5-Iodo-3-Methyl-isothiazole is employed as a key component in the synthesis of insecticides and fungicides, where its antimicrobial attributes help protect crops from pests and diseases.
Used as a Preservative:
5-Iodo-3-Methyl-isothiazole is used as a preservative in various products due to its antimicrobial properties, helping to prevent spoilage and extend the shelf life of different items.
It is crucial to handle 5-Iodo-3-methyl-isothiazole with caution, as it is classified as a hazardous substance with the potential to cause skin and eye irritation. Proper safety measures should be taken during its use to minimize any adverse effects.

Upstream product

• 24340-76-9 3-methyl-5-aminothiazole 
• 71134-43-5 3-methyl-5-aminoisothiazole hydrochloride 

Downstream Products

• 88511-32-4 3-methylisothiazole-5-carboxyaldehyde 
• 24260-24-0 3,5-dimethylisothiazole 

Relevant academic research and scientific papers

PYRIDONE COMPOUND AS C-MET INHIBITOR

Disclosed in the present invention is a type of pyridone compounds as c-met inhibitors, and specifically disclosed is a compound as shown in formula (I) or a pharmaceutically acceptable salt thereof.

BIARYL DERIVATIVE AND MEDICINE CONTAINING SAME

Provided is a compound showing excellent antifungal activity against Trichophyton fungus, which is a major causative microorganism of superficial mycosis, and high effectiveness on diseases caused by Trichophyton fungi. A biaryl derivative represented by the formula (I) or a salt thereof: wherein ring A is an optionally substituted phenyl, or an optionally substituted 5- or 6-membered ring heteroaryl (ring A may be further condensed to form an optionally substituted fused ring); Q is CH2, C=O, NH, O, S or the like; X1, X2 and X3 are CR1 or N; Y is CH or N; Z is CR2b or N; R2a and R2b are each a hydrogen atom, a halogen atom, an optionally substituted C1-C6 alkyl group, a C1-C6 haloalkyl group or the like; R2a and R2b may form, together with carbon atoms bonded thereto, an optionally substituted carbocycle, or an optionally substituted heterocycle.

PHARMACEUTICALS COMPRISING BIARYL DERIVATIVES OR SALTS THEREOF

PROBLEM TO BE SOLVED: To provide compounds with excellent antimycotic activity against Trichophyton. SOLUTION: The invention provides pharmaceuticals comprising biaryl derivatives represented by general formula (I) or salts thereof, where ring A is optionally substituted phenyl or the like; Q is CH2 or the like; X1, X2 and X3 are CR1 or the like; and Y is CH or N. SELECTED DRAWING: None COPYRIGHT: (C)2018,JPOandINPIT

BENZAZEPINE DERIVATIVES, PROCESS FOR THE PREPARATION OF THE SAME AND USES THEREOF

Compounds of the general formula (I): or salts thereof, which exhibit CCR5 antagonism and exert preventive and therapeutic effects against HIV infections: wherein R1 is a 5- to 6-membered aromatic ring which bears a substituent represented by the general formula: R-Z1-X-Z2- (wherein R1 is hydrogen or optionally substituted hydrocarbyl; X is optionally substituted alkylene; and Z1 and Z2 are each a heteroatom) and may be further substituted, with R being optionally bonded to the aromatic ring to form another ring; Y is optionally substituted imino; and R2 and R3 are each optionally substituted aliphatic hydrocarbyl or an optionally substituted hetero-alicyclic group.