2007-97-8

Usage

Uses

Used in Pharmaceutical Industry:
CATECHYLPHOSPHOROTRICHLORIDE is used as a synthetic intermediate for the development of antiviral and antitumor agents, playing a pivotal role in the production of life-saving medications. Its unique properties allow for the creation of complex molecular structures that can target and combat viral and tumor cells effectively.
Used in Pesticide Production:
In the agricultural sector, CATECHYLPHOSPHOROTRICHLORIDE is utilized as a key component in the synthesis of insecticides and herbicides. It contributes to the development of compounds that protect crops from pests and weeds, ensuring higher yields and food security.
Used in Polymer and Material Science:
CATECHYLPHOSPHOROTRICHLORIDE is employed as a reagent in the preparation of phosphorus-containing polymers and materials. Its application in this field is vital for advancing industrial and research applications, where such polymers and materials are essential for various technological and scientific advancements.

InChI:InChI=1/C6H4Cl3O2P/c7-12(8,9)10-5-3-1-2-4-6(5)11-12/h1-4H

Upstream product

• 120-80-9 benzene-1,2-diol 
• 137018-66-7 dichloro(2-methoxyphenoxy)phosphine 
• 10026-13-8 phosphorus pentachloride 
• 71-43-2 benzene 
• 1641-40-3 pyrocatechol phosphorochloridite 

Downstream Products

• 1499-17-8 o-phenylene chlorophosphate 
• 27255-30-7 bis-(2-oxo-2λ⁵-benzo[1,3,2]dioxaphosphol-2-yl)-oxide 
• 130304-82-4 2-Chloro-2-(2,2-dichloro-2-phenyl-ethylidene)-2λ⁵-benzo[1,3,2]dioxaphosphole 
• 19579-02-3 2-phenoxy-2,2'-spirobi<1,3,2λ⁵-benzodioxaphosphole> 
• 60011-08-7 2,2-Dichloro-2-phenoxy-1,3-dioxa-2λ⁵-phospha-indan 
• 96-18-4 1,2,3-trichloropropane 
• 193554-93-7 2,6-dichloro-2-oxo-4-phenylbenzo[e]-1,2λ⁵-oxaphosphorin-3-ene 
• 193554-95-9 2,6-dichloro-2-oxo-4-(4-bromophenyl)benzo[e]-1,2λ⁵-oxaphosphorin-3-ene 
• 814-49-3 diethyl chlorophosphate 
• 618-34-8 1-chlorostyrene 
• 223480-14-6 2-chloro-4-(4-chlorophenyl)-2H-(4-chlorobenzo)[e][1,2]oxaphosphorin-3-ene 2-oxide 
• 7647-01-0 hydrogenchloride 
• 15719-64-9 methylammonium carbonate 
• 1641-40-3 pyrocatechol phosphorochloridite 

Relevant academic research and scientific papers

Synthesis of racemic P-chiral phosphine oxides and phosphonium salts by stepwise reaction of phosphacoumarins with organomagnesium compounds

A new effective synthetic route to the racemic phosphine oxides and phosphonium salts with a P-asymmetric center was developed based on the stepwise reaction of phosphacoumarins with organomagnesium compounds. A selective P–C bond formation was achieved on each step owing to the differences in reactivity of the exocyclic P–Cl or P–O bonds and endocyclic P–O bond of phosphacoumarins. It was found that the P(O)OMgX fragment of the phosphocoumarin salt does not hinder in the substitution reaction at the phosphorus atom accompanied by ring-opening and P–C bond formation.

Synthesis and Antimicrobial Activity of New Dialkyl(diaryl)-2-(5-chloro-2-hydroxyphenyl)-2-(phenylethenyl)pentylphosphonium Salts

New dialkyl(diaryl)-2-(5-chloro-2-hydroxyphenyl)-2-(phenylethenyl)pentylphosphonium salts bearing various substituents at the phosphorus atom were synthesized. Antimicrobial activity of the salts obtained was estimated. Derivatives with 2-methoxyphenyl substituents at the phosphorus atom are most active against grampositive bacteria. Herewith, dibenzyl-substituted phosphonium derivatives possess the best antifungal activity.

CHLORIERUNG VON o-METHOXYPHENYL-DICHLORPHOSPHIT-EINE LITERATURKORREKTUR

o-Methoxyphenyl dichlorophosphit 1 reacts with chlorine to give o-phenylenedioxy-trichlorophosporane 4 and with antimony pentachloride to give o-methoxyphenoxy-trichlorophosphonium-hexachloroantimonate. o-Methoxyphenoxy-tetrachlorophosphorane 2 cannot be isolated. Key words: Dioxytrichlorophosphorane; aryl-oxy-trichlorophosphonium salt; cyclisation.