200803-16-3

Upstream product

• 70-55-3 toluene-4-sulfonamide 
• 1593-60-8 p-toluenesulfonylhydroxylamine 
• 2039-85-2 3-Chlorostyrene 
• 98-59-9 p-toluenesulfonyl chloride 
• 127-65-1 chloroamine-T 
• 55962-05-5 [N-(p-tolylsulfonyl)imino]phenyliodinane 

Downstream Products

• 1573077-48-1 N-(2-(3-chlorophenyl)-2-iodoethyl)-4-methylbenzenesulfonamide 
• 1188273-75-7 N-(2-(3-chlorophenyl)-4-oxo-4-phenylbutyl)-4-methylbenzenesulfonamide 
• 1423077-02-4 2-amino-4-(3-chlorophenyl)-1-tosyl-4,5-dihydro-1H-pyrrole-3-carbonitrile 
• 1423077-03-5 C₁₈H₁₆ClN₃O₂S 
• 1364550-80-0 ethyl (E)-3-(N-(1-(3-chlorophenyl)vinyl)-4-methylphenylsulfonamido)acrylate 
• 1313223-10-7 4-(3-chlorophenyl)-2-methyl-1-(toluene-4-sulfonyl)-4,5-dihydro-1H-imidazole 
• 1313223-22-1 4-(3-chlorophenyl)-2-phenyl-1-(toluene-4-sulfonyl)-4,5-dihydro-1H-imidazole 
• 1294519-99-5 C₂₅H₂₄ClNO₄S₂ 

Relevant academic research and scientific papers

Merging Photoredox/Nickel Catalysis for Cross-Electrophile Coupling of Aziridines with Pyridin-1-ium Salts via Dearomatization

Merging photoredox/nickel catalysis enabling the cross-electrophile coupling of aziridines with pyridin-1-ium salts involving dearomatization for the synthesis of β-(1,4-dihydropyridin-4-yl)-ethylamines, especially including bioactive motif-based analogue

Iron(ii)-catalyzed intermolecular aziridination of alkenes employing hydroxylamine derivatives as clean nitrene sources

The iron-catalyzed intermolecular aziridination of alkenes with hydroxylamine derivatives is described. Using simple iron(ii) sources and readily available ligands, the formal (2 + 1) cycloaddition process proved to be efficient on both styrenes and aliphatic alkenes, providing access to a wide range of aziridines. In these particularly sustainable reaction conditions, yields up to 89% could be obtained, with a catalyst loading which could be lowered to 5 mol% when the reaction was performed on large scale. Preliminary mechanistic studies suggest that both concerted and stepwise pathways are operating in this transformation. This journal is

HKUST-1 Metal Organic Framework as an Efficient Dual-Function Catalyst: Aziridination and One-Pot Ring-Opening Transformation for Formation of β-Aryl Sulfonamides with C-C, C-N, C-S, and C-O Bonds

Metal-organic frameworks (MOFs) are extensively used in catalysis due to their robust structure, well-defined periodic reaction centers, and high porosity. We report Cu3(BTC)2·(H2O)3 (HKUST-1) as an efficient heterogeneous catalyst for aziridination of al

Cycloaddition of α-Diazocarbonyl Compounds and N-Tosylaziridines: Synthesis of Polysubstituted 2 H-1,4-Oxazines through Synergetic Catalysis of AgOTf/Cu(OAc)2

An impressive and new [3 + 3]-cycloaddition of α-diazocarbonyl compounds with N-tosylaziridines via synergetic catalysis of AgOTf and Cu(OAc)2 has been well described, which offers efficient access to highly substituted 2H-1,4-oxazine derivatives. A variety of α-diazocarbonyl compounds and N-tosylaziridines were compatible substrates with convenient operations under mild reaction conditions.

Stereospecific copper-catalyzed domino ring opening and sp3 C-H functionalization of activated aziridines with N-alkylanilines

Copper efficiently catalyzed nucleophilic ring opening, sp3 C-H functionalization, and C-N bond formation in the presence of tert-butyl hydroperoxide to afford functionalized imidazolidines starting from N-sulfonylaziridines and Nalkylanilines. The products were obtained in high optical purities (95 → 99% ee) with excellent functional group tolerance.

Stereoselective Lewis acid mediated (3+2) cycloadditions of N-H- and N-sulfonylaziridines with heterocumulenes

Alkyl and aryl isothiocyanates and carbodiimides are effective substrates in (3+2) cycloadditions with N-sulfonyl-2-substituted aziridines and 2-phenylaziridine for the synthesis of iminothiazolidines and iminoimidazolidines. Additionally, the stereoselec

Intermolecular Alkene Aziridination: An Original and Efficient Cu I···CuI Dinuclear Catalyst Deriving from a Phospha-Amidinate Ligand

Mononuclear and dinuclear CuI complexes 1 and 2 derived from the phospha-amidinate ligands [tBu2P(NSiMe3) 2]- and [Ph2P(NSiMe3) 2]-, respectively, have been

Mechanism of catalytic aziridination with manganese corrole: The often postulated high-valent Mn(V) imido is not the group transfer reagent

The reaction of Arl=NTs (Ar = 2-(tert-butylsulfonyl)benzene and Ts = p-toluenesulfonyl) and (tpfc)Mn (tpfc = 5,10,15-tris(pentafluorophenyl)corrole), 1, affords the high-valent (tpfc)MnV=NTs, 2, on stopped-flow time scale. The reaction proceeds