200942-06-9Relevant academic research and scientific papers
Single-Electron-Transfer-Induced C(sp3)-N Couplings via C-C Bond Cleavage of Cycloketoxime Esters
Shi, Zhuangzhi,Wang, Minyan,Zhao, Binlin
, (2019/08/26)
A practical single-electron-transfer-induced selective C(sp3)-N coupling of cycloketoximes with anilines via C-C bond cleavage under copper-catalytic and synergetic photoredox/copper-catalytic reaction systems has been uncovered. These two powerful and simple protocols demonstrated excellent selectivity and good functional group compatibility without any base or ligand control. Preliminary mechanistic experiments indicated that a radical-mediated process was involved in these transformations.
An efficient synthesis of N-arylputrescines and cadaverines
Link, Natalia P.,Díaz, Jimena E.,Orelli, Liliana R.
scheme or table, p. 751 - 754 (2009/07/18)
We present a two-step, general synthesis of N-aryl-putrescines and cadaverines, by cesium carbonate mediated alkylation of anilines with ω-chloronitriles and subsequent reduction. The cesium-mediated alkylation shows remarkable selectivity towards the mon
