201017-90-5 Usage
General Description
2-methylthiooxazole is a chemical compound with the molecular formula C4H5NOS. It belongs to the oxazole class of compounds which are heterocyclic molecules containing an oxygen and nitrogen atom in a five-membered ring. The "2-methylthio" prefix indicates the presence of a methyl group and a sulfur atom attached to the oxazole ring at the 2-position. 2-methylthiooxazole is known for its versatile reactivity and is utilized in various organic synthesis reactions to create pharmaceutical compounds, agrochemicals, and other functional materials. 2-methylthiooxazole also demonstrates potential as an intermediate in the production of fragrances and flavoring compounds due to its sulfur-containing functional group. Overall, 2-methylthiooxazole is a valuable building block in the development of diverse chemical products.
Check Digit Verification of cas no
The CAS Registry Mumber 201017-90-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,0,1,0,1 and 7 respectively; the second part has 2 digits, 9 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 201017-90:
(8*2)+(7*0)+(6*1)+(5*0)+(4*1)+(3*7)+(2*9)+(1*0)=65
65 % 10 = 5
So 201017-90-5 is a valid CAS Registry Number.
201017-90-5Relevant articles and documents
Monosubstituted Oxazoles. 1. Synthesis of 5-Substituted Oxazoles by Directed Alkylation
Shafer, Cynthia M.,Molinski, Tadeusz F.
, p. 551 - 555 (1998)
A general method is presented for synthesis of 2-(methylthio)-5-substituted oxazoles 2. Deprotonation of the readily available 2-(methylthio)oxazole (1) with n-BuLi occurs smoothly in the presence of TMEDA and regiospecifically at C5. The organometallic 1a added rapidly to aldehydes and other electrophiles to provide 5-substituted-2-(methylthio)oxazoles in very good to excellent yields. Reductive removal of the MeS group gave the desired 5-monosubstituted oxazoles 3 in good yield.
Nickel-catalyzed synthesis of oxazoles via C-S activation
Lee, Kyoungsoo,Counceller, Carla M.,Stambuli, James P.
supporting information; experimental part, p. 1457 - 1559 (2009/08/08)
The synthesis of 2-substituted oxazoles is achieved via nickel-catalyzed cross-coupling reaction of 2-methylthio-oxazole and various organozinc reagents. An extension of this method is demonstrated with a chemoselective, one-pot synthesis of unsymmetrical
