201034-46-0

Upstream product

• 102429-07-2 2-bromo-2',4'-difluoroacetophenone 
• 201034-35-7 2-(2-acetoxyethylthio)-2,2,2',4'-tetrafluoroacetophenone 
• 201034-31-3 α-[(β'-acetoxyethyl)thio]-2',4'-difluoroacetophenone 
• 201034-30-2 2',4'-difluoro-2-[(2-hydroxyethyl)thio]acetophenone 

Downstream Products

• 201034-56-2 1-(2-acetoxyethyl)sulfonyl-2-(2,4-difluorophenyl)-1,1-difluoro-3-(1H-1,2,4-triazol-1-yl)propan-2-ol 
• 201034-54-0 2-(2,4-difluorophenyl)-1,1-difluoro-1-[(2-hydroxyethyl)thio]-3-(1H-1,2,4-triazol-1-yl)-2-propanol 

Relevant academic research and scientific papers

New antifungal 1,2,4-triazoles with difluoro(substituted sulfonyl)methyl moiety

New 1,2,4-triazoles (2) having a difluoro(substituted sulfonyl)methyl moiety were designed and synthesized via α,α-difluoro-α-(substituted thio)acetophenones (3). Compounds (2) showed potent antifungal activities against C. albicans, C. krusei, A. flavus