Preparation of difluoro analogs of CCGs and their pharmacological evaluations

DOI: 10.1016/S0960-894X(98)00338-2

Source and publish data:

Bioorganic and Medicinal Chemistry Letters p. 1979 - 1984 (1998)

Update date:2022-09-26

Topics: Preparation

Authors:

Shibuya, Akira

Sato, Azusa

Taguchi, Takeo

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Article abstract of DOI:10.1016/S0960-894X(98)00338-2

All the stereoisomers of 2-(2-carboxy-3,3-difluorocyclopropyl)glycines (F₂CCGs) were synthesized in enantiomerically pure forms using (R)-2,3-O- isopropyl-ideneglyceraldehyde as a chiral precursor. L-F₂CCG-I, one of the stereoisomers

Full text of DOI:10.1016/S0960-894X(98)00338-2

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