201279-54-1Relevant academic research and scientific papers
Optically active cantharidin analogues possessing selective inhibitory activity on Ser/Thr protein phosphatase 2B (calcineurin): Implications for the binding mode
Baba, Yoshiyasu,Hirukawa, Nozomu,Sodeoka, Mikiko
, p. 5164 - 5170 (2005)
Cantharidin is well known as a potent serine/threonine protein phosphatase 1 and 2A (PP1 and PP2A) inhibitor, with less potent inhibitory activity for PP2B, which regulates T-cell proliferation. We synthesized and evaluated four optically pure stereoisome
The configurational assignment of the optically active 5-(1-hydro- peroxyethyl)-3-ethoxycarbonyl-2-methylfuran and its alcohol by exciton- coupled circular dichroism (ECCD)
Adam, Waldemar,Humpf, Hans-Ulrich,Korb, Marion N.,Schreier, Peter
, p. 3555 - 3558 (1997)
The absolute configuration of the furan-derived hydroperoxide 1 and its alcohol 2, readily available in optically active form by kinetic resolution of the racemic hydroperoxide with horseradish peroxidase (HRP), was determined by the exciton-coupled circular dichroism (ECCD) method on their 2-naphthoate derivatives 4.
