862902-41-8Relevant academic research and scientific papers
Optically active cantharidin analogues possessing selective inhibitory activity on Ser/Thr protein phosphatase 2B (calcineurin): Implications for the binding mode
Baba, Yoshiyasu,Hirukawa, Nozomu,Sodeoka, Mikiko
, p. 5164 - 5170 (2007/10/03)
Cantharidin is well known as a potent serine/threonine protein phosphatase 1 and 2A (PP1 and PP2A) inhibitor, with less potent inhibitory activity for PP2B, which regulates T-cell proliferation. We synthesized and evaluated four optically pure stereoisome
