201341-14-2

Usage

Uses

Used in Chemical Synthesis:
Acetaldehyde, [(4-bromophenyl)methoxy]is used as a reagent in chemical synthesis for its ability to participate in a variety of organic reactions, contributing to the formation of complex molecules and compounds.
Used in Pharmaceutical Production:
In the pharmaceutical industry, Acetaldehyde, [(4-bromophenyl)methoxy]is utilized as an intermediate in the production of various drugs, playing a crucial role in the synthesis of medicinal compounds.
Used in Solvent Applications:
Acetaldehyde, [(4-bromophenyl)methoxy]is employed as a solvent in different industries due to its capacity to dissolve a wide range of substances, facilitating processes that require solubility of specific compounds.
Used in Laboratory Research:
Acetaldehyde, [(4-bromophenyl)methoxy]is also used in laboratory research settings for the study of chemical reactions and the development of new methodologies in organic chemistry, where its unique properties can be explored and harnessed.

Upstream product

• 400837-92-5 2-(4-bromobenzyloxy)ethanol 
• 589-15-1 1-bromomethyl-4-bromobenzene 
• 787576-31-2 1-bromo-4-(2,2-diethoxy-ethoxymethyl)-benzene 

Downstream Products

• 212205-69-1 (S)-2-(4-Bromo-benzyloxymethyl)-2,3-dihydro-pyran-4-one 
• 434308-60-8 (3S,4R)-5-(4-bromobenzyloxy)-4-hydroxy-3-methylpent-1-ene 
• 212205-70-4 ((1R,2R)-2-Methoxymethoxy-1-vinyl-tetradecyloxy)-acetic acid (2S,4S)-2-(4-bromo-benzyloxymethyl)-3,4-dihydro-2H-pyran-4-yl ester 
• 434308-95-9 [(1S,2S)-1-(4-Bromo-benzyloxymethyl)-2-methyl-but-3-enyl]-[1-(4-methoxy-phenyl)-meth-(E)-ylidene]-amine 
• 434308-80-2 C₃₄H₅₃BrN₄O₇Si 
• 434309-04-3 (3R,4aS,6S,7R,8S)-8-(4-Bromo-benzyloxymethyl)-3-[(S)-(tert-butyl-dimethyl-silanyloxy)-(2,6-dimethoxy-pyrimidin-4-yl)-methyl]-6-hydroxy-7-methyl-octahydro-pyrido[1,2-c]pyrimidin-1-one 

Relevant academic research and scientific papers

Scalable Formal Synthesis of (-)-Quinocarcin

A scalable and unified strategy is described for the synthesis of (-)-quinocarcin, an important tetrahydroisoquinoline antitumor alkaloid. The strategy allows the practical formal synthesis of (-)-quinocarcin in 13 steps and 4.8% overall yield using N-pht

Nickel-Catalyzed Alkyl-Alkyl Cross-Electrophile Coupling Reaction of 1,3-Dimesylates for the Synthesis of Alkylcyclopropanes

Cross-electrophile coupling reactions of two Csp3-X bonds remain challenging. Herein we report an intramolecular nickel-catalyzed cross-electrophile coupling reaction of 1,3-diol derivatives. Notably, this transformation is utilized to synthesize a range of mono- and 1,2-disubstituted alkylcyclopropanes, including those derived from terpenes, steroids, and aldol products. Additionally, enantioenriched cyclopropanes are synthesized from the products of proline-catalyzed and Evans aldol reactions. A procedure for direct transformation of 1,3-diols to cyclopropanes is also described. Calculations and experimental data are consistent with a nickel-catalyzed mechanism that begins with stereoablative oxidative addition at the secondary center.

Total synthesis of (-)-7-epicylindrospermopsin, a toxic metabolite of the freshwater cyanobacterium Aphanizomenon ovalisporum, and assignment of its absolute configuration

(Chemical Equation Presented) The Z and E nitrones 38 and 39 from condensation of aldehyde 20 with hydroxylamine 36 underwent intramolecular dipolar cycloaddition to give the substituted 1-aza-7-oxobicyclo[2.2.1] heptanes 40 and 41 in a ratio of 2:1, respectively. Reductive N-O bond cleavage of 40 followed by carbonylation gave cyclic urea 47 in which inversion of the secondary alcohol was effected via an oxidation-reduction sequence. After conversion of the p-bromobenzyl ether 50 to azide 54, activation of the cyclic urea as its O-methylisourea and reduction of the azide led to spontaneous cyclization to afford the tricyclic nucleus 59 of cylindrospermopsin. Global deprotection, including hydrolysis of the 2,4-dimethyoxypyrimidine appendage to a uracil, and then monosulfation of the resultant diol 60 afforded a substance identical with natural (-)-7-epicylindrospermopsin (1). The asymmetric synthesis of (-)-7-epicylindrospermopsin defines its absolute configuration as 7S,8R,10S,12S,13R,14S.

ISOQUINOLINE-5-SULFONIC ACID AMIDES AS INHIBITORS OF AKT (PROTEIN KINASE B)

The present invention relates to compounds Formula (I): as inhibitors of AKT activity, which are useful for the treatment of susceptible neoplasms and viral infections.

Asymmetric synthesis of epicylindrospermopsin via intramolecular nitrone cycloaddition. Assignment of absolute configuration

A synthesis of (-)-epicylindrospermopsin (2) was completed that establishes its absolute configuration and corroborates the corrected structural assignment previously made to this toxin by Weinreb et al. The hydroxylamine 3, prepared from 4-bromobenzyloxy